2. Gene
  3. Hdac7 - histone deacetylase 7 Gene

Hdac7 - histone deacetylase 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HD7; HD7a; Hdac7a; mFLJ00062; 5830434K02Rik

Gene ID: 56233 | Gene type: protein coding

About Hdac7

Chromosome 15: 97,690,545-97,742,383 reverse strand.GRCm39:CM001008.3

This gene has 13 transcripts (splice variants), 263 orthologues, 10 paralogues and is associated with 16 phenotypes. Broad expression in thymus adult (RPKM 141.4), lung adult (RPKM 54.7) and 16 other tissues.

Summary

Enables chromatin binding activity and transcription corepressor activity. Acts upstream of or within cell-cell junction assembly; negative regulation of transcription by RNA polymerase II; and vasculogenesis. Predicted to be located in cytosol and nucleus. Predicted to be part of histone deacetylase complex. Is expressed in adrenal gland; embryo; eye; inner ear; and otocyst. Orthologous to human HDAC7 (histone deacetylase 7). [provided by Alliance of Genome Resources, Apr 2022]

Hdac7 Products(9)

mRNA Protein Name
NM_001204276.1 NP_001191205.1 histone deacetylase 7 isoform 2
NM_019572.3 NP_062518.2 histone deacetylase 7 isoform 4
NM_001378971.1 NP_001365900.1 histone deacetylase 7 isoform 9
NM_001204277.1 NP_001191206.1 histone deacetylase 7 isoform 3
NM_001204280.1 NP_001191209.1 histone deacetylase 7 isoform 7
NM_001204281.1 NP_001191210.1 histone deacetylase 7 isoform 8
NM_001204275.1 NP_001191204.1 histone deacetylase 7 isoform 1
NM_001204279.1 NP_001191208.1 histone deacetylase 7 isoform 6
NM_001204278.1 NP_001191207.1 histone deacetylase 7 isoform 5

Hdac7 Protein Structure

PHA03247

PHA03247: cl33720 (121 - 524)

HDAC7

HDAC7: cd10008 (543 - 918)

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  • 975 a.a.
Protein Preferred Names Protein Names

histone deacetylase 7

histone deacetylase 7A

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10221 Vorinostat Inhibitor 99.95% Yes
HY-13322 Pracinostat Inhibitor 99.82% Yes
Clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Phase
HY-14842B Givinostat hydrochloride monohydrate Inhibitor ≥98.0% Phase 3
HY-14842 Givinostat Inhibitor 98.05% Phase 3
HY-14842A Givinostat hydrochloride Inhibitor / Phase 3
HY-16026 Ricolinostat Inhibitor 99.83% Phase 2
HY-15433 Quisinostat Inhibitor 98.34% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-15433A Quisinostat dihydrochloride Inhibitor 98.28% Phase 2
HY-10223 CUDC-101 Inhibitor 99.19% Phase 1
HY-15994 Citarinostat Inhibitor 99.30% Phase 1
Pre-clinical Phase
Bioactive Molecules (22)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18361 TMP195 Inhibitor 99.57% Unkown
HY-18360 TMP269 Inhibitor 98.05% Unkown
HY-13428 Tubacin Inhibitor 95.50% Unkown
HY-16699 Nexturastat A Inhibitor 99.03% Unkown
HY-115475 SW-100 Inhibitor 99.59% Unkown
HY-119939 CHDI-390576 Inhibitor 98.07% Unkown
HY-126330 SS-208 Inhibitor 99.00% Unkown
HY-149285 NT160 Inhibitor 99.58% Unkown
HY-117554 BRD9757 Inhibitor 99.75% Unkown
HY-146678 HDAC6-IN-5 Inhibitor / Unkown
HY-150109 Purinostat mesylate Inhibitor / Unkown
HY-146679 HDAC6-IN-6 Inhibitor / Unkown
HY-162319 Tubulin/HDAC-IN-4 Inhibitor / Unkown
HY-15144B (S)-Trichostatin A Inhibitor / Unkown
HY-150595 HDAC6-IN-10 Inhibitor / Unkown
HY-150774 HDAC6/HSP90-IN-2 Inhibitor / Unkown
HY-157740 XSJ-10 Inhibitor / Unkown
HY-149208 HDAC-IN-53 Inhibitor / Unkown
HY-152226 MC2590 Inhibitor / Unkown
HY-149283 JAK/HDAC-IN-2 Inhibitor / Unkown
HY-146684 HDAC-IN-36 Inhibitor / Unkown
HY-152225 MC2625 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hdac7 NCBI NCBI:51564