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91694

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By Targets:	Glucokinase (1) mAChR (1) Nucleoside Antimetabolite/Analog (2) Prostaglandin Receptor (1) Reference Standards (1) Thymidylate Synthase (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Metabolic Disease (1)

Inhibitors & Agonists

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10821

Raltitrexed 10+ Cited Publications ZD1694; D1694; ICI-D1694	Thymidylate Synthase Nucleoside Antimetabolite/Analog	Cancer
Raltitrexed is an antimetabolite agent used in chemotherapy, acting by inhibiting thymidylate synthase.

HY-12614

AMG-1694	Glucokinase	Metabolic Disease
AMG-1694 is a potent glucokinase–glucokinase regulatory protein (GK-GKRP) disruptors and promotes the dissociation of the GK-GKRP complex with an IC₅₀ of 7 nM, indirectly increasing GK enzymatic activity. AMG-1694 potently reverses the inhibitory effect of GKRP on GK activity and promotes GK translocation. AMG-1694 normalizes blood glucose levels in several rodent models of diabetes and lowes blood glucose restricted to diabetic and not normoglycaemic animals .

HY-10821R

Raltitrexed (Standard) ZD1694 (Standard); D1694 (Standard); ICI-D1694 (Standard)	Thymidylate Synthase Nucleoside Antimetabolite/Analog Reference Standards	Cancer
Raltitrexed (Standard) is the analytical standard of Raltitrexed. This product is intended for research and analytical applications. Raltitrexed is an antimetabolite agent used in chemotherapy, acting by inhibiting thymidylate synthase.

HY-114846

Ro 22-9194	Prostaglandin Receptor	Cardiovascular Disease
Ro 22-9194 inhibits aggregation and thromboxane Az (TXA2) synthetase activity in rabbit and human platelets. Ro 22-9194 has a potent inhibitory action against various types of model arrhythmias. Ro 22-9194 has non-cholinergic cardiac depressant properties with its vasodilating action .

HY-113692

*AZD-9164* bromide**	mAChR	Others
AZD-9164 (bromide) is a long-acting muscarinic M3 antagonist. AZD-9164 (bromide) is promising for research of airways diseases, such as chronic obstructive pulmonary disease (COPD) or asthma .

Host:	Mouse (3) Rabbit (3)
Reactivity:	Human (3) mouse (1) Rat (2) Mouse (3) rat (1) human (3)
Application:	IHC-P (3) ICC/IF (5) IF-Tissue (3) IP (3) IHC-F (2) WB (6) FC (1) ELISA (3)
Isotype:	IgG (3) IgG1 (2) IgG2a (1)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P89820

	PJA1 Antibody (YA9164)	WB, IP, ELISA	human
	PJA1 Antibody (YA9164) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PJA1.

HY-P89850

	Sgo1 Antibody (YA9194)	WB, ICC/IF, IF-Tissue, IP, ELISA	human, mouse, rat
	Sgo1 Antibody (YA9194) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Sgo1.

HY-P89825

	Thrombospondin 5 Antibody (YA9169)	WB, ICC/IF, IF-Tissue, IP, ELISA	human
	Thrombospondin 5 Antibody (YA9169) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Thrombospondin 5.

HY-P81949

	Lipoamide Dehydrogenase Antibody (YA1694) Diaphorase; Dihydrolipoamide dehydrogenase; DLDD; DLDH; GCSL; LAD; lipoamide dehydrogenase; Lipoamide reductase; Lipoyl dehydrogenase; PHE3	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Lipoamide Dehydrogenase Antibody (YA1694) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Lipoamide Dehydrogenase.

HY-P81949A

	Lipoamide Dehydrogenase Antibody (YA1694)(PBS only) Diaphorase; Dihydrolipoamide dehydrogenase; DLDD; DLDH; GCSL; LAD; lipoamide dehydrogenase; Lipoamide reductase; Lipoyl dehydrogenase; PHE3	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Lipoamide Dehydrogenase Antibody (YA1694) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Lipoamide Dehydrogenase.

HY-P810374

	HMGA2 Antibody (YA9694) HMGA 2, BABL, High mobility group (nonhistone chromosomal) protein isoform I C, High mobility group (nonhistone chromosomal) protein isoform IC, High Mobility Group AT hook 2, High Mobility Group AT hook protein 2, High mobility group AT-hook protein 2, High mobility group protein HMGI C, High mobility group protein HMGI-C, High mobility group protein HMGIC	WB, ICC/IF, IHC-P, FC, IF-Tissue	Human, Mouse
	HMGA2 Antibody (YA9694) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to HMGA2.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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