CC-M-1
CC-M-1 is a potent and selective PI3K/mTOR inhibitor. CC-M-1 inhibits PI3Kα/β/γ/δ and mTOR with IC50 values of 0.68, 1.02, 1.03, 8.03, and 15 nM, respectively. CC-M-1 inhibits the proliferation of colorectal cancer cell lines, including HCT-116 (IC50 = 0.38 μM) and HT-29 (IC50 = 1.70 μM). CC-M-1 can be used for colorectal cancer (CRC) research.
For research use only. We do not sell to patients.
- CAS No.: 3079943-00-0
- Formula: C28H29F2N9O4S
- Molecular Weight:625.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PI3Kα 0.68 nM (IC50) |
PI3Kβ 1.02 nM (IC50) |
PI3Kγ 1.03 nM (IC50) |
PI3Kδ 8.03 nM (IC50) |
mTOR 15 nM (IC50) |
Chemical Information
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CAS No. 3079943-00-0
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Molecular Weight 625.65
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Formula C28H29F2N9O4S
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SMILES
COC1=C(C=C(C=N1)C2=NN3C(C4=CN(N=N4)CCCN5CCCC(C5)O)=CN=C3C=C2)NS(=O)(C6=C(C=C(C=C6)F)F)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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