Copy Link Print Information

Lenalidomide hydrochloride

(別名: CC-5013 hydrochloride)
63 Cited Publications
カスタマーレビュー

Based on 63 publication(s) in Google Scholar

Lenalidomide hydrochloride (CC-5013 hydrochloride), a derivative of Thalidomide, acts as molecular glue. Lenalidomide hydrochloride is an orally active immunomodulator. Lenalidomide hydrochloride (CC-5013 hydrochloride) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hydrochloride (CC-5013 hydrochloride) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • CAS 番号: 1243329-97-6
  • 分子式: C13H14ClN3O3
  • 分子量:295.72
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Lenalidomide hydrochloride Chemical Structure
    Lenalidomide hydrochloride 構造式
  • Experimental Validation Results for Lenalidomide hydrochloride
  • Experimental Validation Results for Lenalidomide hydrochloride
  • Experimental Validation Results for Lenalidomide hydrochloride
  • Experimental Validation Results for Lenalidomide hydrochloride
  • Experimental Validation Results for Lenalidomide hydrochloride
CAS 番号: 1243329-97-6
容量
価格（税別）
在庫状況
数量
Amount: USD 0.00
Please select quantity
or
or

* アイテムを追加する前、数量をご選択ください

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Lenalidomide hydrochloride:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
  • 生物活性
  • 化学情報
  • プロトコル
  • 純度とドキュメンテーション
  • 参考文献
  • Help & FAQs
Top Publications Citing

Use of MCE Products

MedChemExpress（MCE）の使用を引用している文献 Lenalidomide hydrochloride

More
Customer Validation & Images
WB
  • WB
  • WB
  • WB
  • WB
  • WB

Ligands for E3 Ligase アイソフォーム固有の製品をすべて表示

More
Keywords
MOQ
Minimum order quantity
100 mg

お問い合わせ 在庫あり

Other size
お問い合わせ
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress ログイン
Register
Sign in to MedChemExpress
新規会員登録

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Lenalidomide hydrochloride Chemical Structure
    Lenalidomide hydrochloride Chemical Structure
    1/16
  • 1/16

    Lenalidomide hydrochloride purchased from MedChemExpress. Usage Cited in: Nat Cancer. 2022 May;3(5):595-613. [Abstract]

    Customer Validation
     Western blot analysis for IKAROS, CK1α and MENIN protein following treatment of MV4;11 human MLL-r AML cell line for 5 hours with increasing doses of Thalidomide, lenalidomide, Pomalidomide and iberdomide (10,100, 1000 nM), using ACTIN as a loading control.

  • 1/16

    Lenalidomide hydrochloride purchased from MedChemExpress. Usage Cited in: Cell. 2018 Sep 20;175(1):171-185.e25. [Abstract]

    Customer Validation
     WB analysis of MV4-11 cells treated for 6.5 hr with Lenalidomide, BTX161, A51, or A86 at the indicated concentrations or DMSO.

  • 1/16

    Lenalidomide hydrochloride purchased from MedChemExpress. Usage Cited in: Oncol Rep. 2018 Jun;39(6):2873-2880. [Abstract]

    Customer Validation
     Representative western blot membranes showing the expression levels of NF-κB p-p65 and H3 in nuclear protein and of NF-κB p65 and β-actin in total protein. β-actin and H3 are used as internal controls.

  • 1/16

    Lenalidomide hydrochloride purchased from MedChemExpress. Usage Cited in: Elife. 2018 Aug 1;7:e38430. [Abstract]

    Customer Validation
     H9 hESC are treated with increasing concentrations of Thalidomide, Lenalidomide, Pomalidomide, or DMSO as a control. Following 24 h of incubation, SALL4 and GAPDH protein levels are assessed by western blot analysis.

  • 1/16

    Lenalidomide hydrochloride purchased from MedChemExpress. Usage Cited in: Nat Commun. 2017 May 22;8:15398. [Abstract]

    Customer Validation
     HEK293T cells are treated with 50 μg/mL Cycloheximide and increasing concentrations of Lenalidomide, Thalidomide or with DMSO, and cells are incubated for 6 h. ZFP91 and GAPDH levels are detected using anti-ZFP91 or anti-GAPDH immunoblotting.

  • Lenalidomide hydrochloride