DB0662
Based on 1 Customer Validation
DB0662 is a multi-target kinase-directed PROTAC degrader, targeting kinases including PTK2B, MAPK9, BLK, CSK, LIMK1, etc.
(Pink: Ligands for Target Protein for PROTAC ligand (HY-176367); Blue: Cereblon ligand (HY-14658); Black: linker).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.66%
- CAS 番号: 2769753-51-5
- 分子式: C47H44F3N11O7
- 分子量:931.92
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
PROTACs アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 2769753-51-5
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性状 Solid
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分子量 931.92
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分子式 C47H44F3N11O7
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Color Light yellow to yellow
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SMILES
O=C(C1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(C)C(N3C(N(C)C4=NC(NC5=CN=C(N6CCN(CCCOC7=CC=CC(C(N8C9C(NC(CC9)=O)=O)=O)=C7C8=O)CC6)C=C5)=NC=C4C3)=O)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (53.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0731 mL | 5.3653 mL | 10.7305 mL | 26.8263 mL |
| 5 mM | 0.2146 mL | 1.0731 mL | 2.1461 mL | 5.3653 mL | |
| 10 mM | 0.1073 mL | 0.5365 mL | 1.0731 mL | 2.6826 mL | |
| 15 mM | 0.0715 mL | 0.3577 mL | 0.7154 mL | 1.7884 mL | |
| 20 mM | 0.0537 mL | 0.2683 mL | 0.5365 mL | 1.3413 mL | |
| 25 mM | 0.0429 mL | 0.2146 mL | 0.4292 mL | 1.0731 mL | |
| 30 mM | 0.0358 mL | 0.1788 mL | 0.3577 mL | 0.8942 mL | |
| 40 mM | 0.0268 mL | 0.1341 mL | 0.2683 mL | 0.6707 mL | |
| 50 mM | 0.0215 mL | 0.1073 mL | 0.2146 mL | 0.5365 mL |