Flavipucine
Flavipucine (Flavipucin), a glutarimide antibiotic, is found in the strain of Aspergillus flavipes F-2090/7. Flavipucine has antibacterial activity against B. subtilis. Flavipucine has antiprotozoal activity. Flavipucine has cytotoxic activity against several cancer cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 38473-18-6
- 分子式: C12H15NO4
- 分子量:237.25
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
1.6 μM
Compound: (-)-1
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Cytotoxicity against human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by WST8 dye based assay
Cytotoxicity against human HL60 cells assessed as reduction in cell viability incubated for 48 hrs by WST8 dye based assay
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[PMID: 30935798] |
化学情報
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CAS 番号 38473-18-6
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分子量 237.25
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分子式 C12H15NO4
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SMILES
CC(C)CC([C@H]1[C@]2(C(C=C(NC2=O)C)=O)O1)=O
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別名
Flavipucin
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Kusakabe Y, et al. Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1390-1394. [Content Brief]
[2]. Boya P CA, et al. Antiprotozoal Natural Products from Endophytic Fungi Associated with Cacao and Coffee. Metabolites. 2024 Oct 25;14(11):575. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Flavipucine 関連分類
HY-N14364 関連分類
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