Patuletin
Patuletin is a flavonol, that can be isolated from the flowers of Tagetes patula. Patuletin shows anti-proliferative activity against cancer cells. Patuletin causes significant nuclear fragmentation and has a great capacity to induce caspase-3 activation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 519-96-0
- 分子式: C16H12O8
- 分子量:332.26
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Caspase アイソフォーム固有の製品をすべて表示
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生物活性
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Caspase 3 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
10.1 μg/mL
Compound: 11
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Antioxidant activity in human HL60 cells assessed as reduction of cytochrome-c release
Antioxidant activity in human HL60 cells assessed as reduction of cytochrome-c release
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[PMID: 10650074] |
Patuletin (0-100 μg/mL, 24 h) shows anti-proliferative activity against cancer cells[2].
Patuletin induces apoptosis in the CaSki, MDA-MB-231, and SK-Lu-1 cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:CaSki, MDA-MB-231 and SK-Lu-1
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Concentration:6, 12, 25, 50 and 100 μg/mL
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Incubation Time:24 h
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Result:Showed a dose-dependent proliferation inhibition, with IC50 values of 37, 86, and 18 μg/mL for CaSki, MDA-MB-231 and SK-Lu-1 cells, respectively.
化学情報
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CAS 番号 519-96-0
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分子量 332.26
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分子式 C16H12O8
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SMILES
O=C1C(O)=C(C2=CC(O)=C(O)C=C2)OC3=CC(O)=C(C(O)=C13)OC
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Patuletin 関連分類
HY-N12503 関連分類
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