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Cat. No.: HY-156745

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PROTAC DDa-1

PROTAC DDa-1 is a potent BTK degrader (DC₅₀: 90 nM).
(Pink: Btk ligand (HY-107447); Blue: Cereblon ligand (HY-149934); Black: linker).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3036944-98-3
화학식: C₆₀H₇₇Cl₂N₁₃O₃S
분자량:1131.31

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

PROTAC DDa-1 Chemical Structure

CAS No.: 3036944-98-3

사이즈

가격

재고

수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

PROTAC DDa-1 is a potent BTK degrader (DC₅₀: 90 nM)^[1]. (Pink: Btk ligand (HY-107447); Blue: Cereblon ligand (HY-149934); Black: linker).

All PROTACs Isoforms :

Chemical Information

CAS No. 3036944-98-3
분자량 1131.31
화학식 C₆₀H₇₇Cl₂N₁₃O₃S
SMILES

O=C(N1CCN(C2=CC=C3C(N=C(C4(C5=CC=C(Cl)C=C5)CCCCC4)N=C3NCCN)=C2)CC1)CCCCCCCN6CCC(OC7CCN(C8=CC(NC9=NC=C(C(NC%10=C(C)C=CC=C%10Cl)=O)S9)=NC(C)=N8)CC7)CC6
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Schröder M, et al. DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nat Commun. 2024 Jan 4;15(1):275. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
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PROTAC DDa-1

All PROTACs Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PROTAC DDa-1 Related Classifications

HY-156745 Related Classifications