YVAD-CHO
YVAD-CHO is an interleukin-1β converting enzyme (ICE, caspase 1) inhibitor (Ki: 0.76 nM). YVAD-CHO inhibits mature IL-1β production. YVAD-CHO partially delays motoneurone death in lesioned facial nerve mice.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 153604-27-4
- 화학식: C21H30N4O7
- 분자량:450.49
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
All Caspase Isoforms
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Biological Activity
제품 설명
IC50 & Target
ICE[1]
Chemical Information
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CAS No. 153604-27-4
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분자량 450.49
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화학식 C21H30N4O7
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Sequence
Tyr-Val-Ala-Asp-{CHO}
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Sequence Shortening
YVAD-{CHO}
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. de Bilbao F, Dubois-Dauphin M. Acute application of an interleukin-1 beta-converting enzyme-specific inhibitor delays axotomy-induced motoneurone death. Neuroreport. 1996 Nov 25;7(18):3051-4. [Content Brief]
[2]. Laliberte RE, et al. ATP treatment of human monocytes promotes caspase-1 maturation and externalization. J Biol Chem. 1999 Dec 24;274(52):36944-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
YVAD-CHO Related Classifications
HY-P5890 Related Classifications
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