KRASG12C IN-16
KRASG12C IN-16 (Compound SK-17) is a selective, covalent and an orally active KRASG12C inhibitor. KRASG12C IN-16 induces Apoptosis. KRASG12C IN-16 effectively prevents the activation of MAPK and PI3K/mTOR signaling pathways. KRASG12C IN-16 displays anti-tumor activity against pancreatic cancer.
For research use only. We do not sell to patients.
- Formula: C28H35ClN8O2
- Molecular Weight:551.08
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
KRAS(G12C) |
Chemical Information
-
Molecular Weight 551.08
-
Formula C28H35ClN8O2
-
SMILES
ClC1=C(C(NC(N2CC3=NC(N4CC(C4)N(C)C)=NC(N5C6CN(CC5CC6)C(C=C)=O)=C3C2)=O)=CC=C1)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)