Cat. No.: HY-135115

Oleuropein Aglycone

(Synonyms: 3,4-DHPEA-EA)

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

Oleuropein Aglycone (3,4-DHPEA-EA) is a polyphenol and the aglycone form of oleuropein (HY-N0292), formed by enzymatic, acidic or acetylated hydrolysis of oleuropein. Dietary intake of oleuropein Aglycone (50 mg/kg diet) increases the number of neuronal autophagic vesicles, reverses cognitive deficits in the TgCRND8 transgenic mouse model of Alzheimer's disease, and reduces the levels of histone deacetylase 2 (HDAC2) in the cortex and hippocampus. Oleuropein Aglycone increases urinary norepinephrine, interscapular brown adipose tissue epinephrine, and UCP1 protein levels, and reduced plasma leptin levels and total abdominal adipose tissue weight in a rat model of high-fat diet-induced obesity. Oleuropein Aglycone also reduced lung neutrophil infiltration, lipid peroxidation, and IL-1β levels in a mouse model of carrageenan-induced pleurisy.

For research use only. We do not sell to patients.

Purity: 98.46%
CAS No.: 31773-95-2
Formula: C₁₉H₂₂O₈
Molecular Weight:378.37

Storage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Oleuropein Aglycone Chemical Structure

CAS No.: 31773-95-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All α-synuclein Isoforms :

All Adrenergic Receptor Isoforms :

All HDAC Isoforms :

Chemical Information

CAS No. 31773-95-2
Appearance Oil
Molecular Weight 378.37
Formula C₁₉H₂₂O₈
Color Off-white to light yellow
SMILES

O=C(OCCC1=CC=C(O)C(O)=C1)C[C@H]2/C([C@H](O)OC=C2C(OC)=O)=C\C
Synonyms

3,4-DHPEA-EA
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (1)

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Journal Impact Factor

Nutraceuticals

2026 Jun;6(2):24.

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (132.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.6429 mL

13.2146 mL

26.4292 mL

5 mM

0.5286 mL

2.6429 mL

5.2858 mL

10 mM

0.2643 mL

1.3215 mL

2.6429 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xu, et al. Structure properties, acquisition protocols, and biological activities of oleuropein aglycone. Front. Chem. 6, 239 (2018).

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.6429 mL	13.2146 mL	26.4292 mL	66.0729 mL
	5 mM	0.5286 mL	2.6429 mL	5.2858 mL	13.2146 mL
	10 mM	0.2643 mL	1.3215 mL	2.6429 mL	6.6073 mL
	15 mM	0.1762 mL	0.8810 mL	1.7619 mL	4.4049 mL
	20 mM	0.1321 mL	0.6607 mL	1.3215 mL	3.3036 mL
	25 mM	0.1057 mL	0.5286 mL	1.0572 mL	2.6429 mL
	30 mM	0.0881 mL	0.4405 mL	0.8810 mL	2.2024 mL
	40 mM	0.0661 mL	0.3304 mL	0.6607 mL	1.6518 mL
	50 mM	0.0529 mL	0.2643 mL	0.5286 mL	1.3215 mL
	60 mM	0.0440 mL	0.2202 mL	0.4405 mL	1.1012 mL
	80 mM	0.0330 mL	0.1652 mL	0.3304 mL	0.8259 mL
	100 mM	0.0264 mL	0.1321 mL	0.2643 mL	0.6607 mL

Keywords

Oleuropein Aglycone

1 Cited Publications

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Oleuropein Aglycone

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Publications Citing Use of MedChemExpress (MCE) Oleuropein Aglycone

All α-synuclein Isoforms

All Adrenergic Receptor Isoforms

All HDAC Isoforms

Biological Activity

Chemical Information

Publications (1)

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

Oleuropein Aglycone Related Classifications

HY-135115 Related Classifications