302 Results for "

superoxide

" in MedChemExpress (MCE) Product Catalog:
Products (302)

302 Results for "superoxide" in MCE Product Catalog:

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Cat. No.: HY-110282
CAS No.: 890888-12-7
Purity:  99.62%
S3QEL-2, a suppressor of superoxide production from mitochondrial complex III, potently and selectively suppresses site IIIQo superoxide production (IC50=1.7 μM). S3QEL-2 does not affect oxidative phosphorylation, and normal electron flux. S3QEL-2 inhibits HIF-1α accumulation .
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Cat. No.: HY-N4084
CAS No.: 271579-11-4
Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities .
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Cat. No.: HY-Y0651
CAS No.: 7757-83-7
Sodium sulfite is an inorganic salt used as an antioxidant and preservative. Sodium sulfite is also used in sulfonation and sulfomethylation reactions. Sodium sulfite can also be used as a bleaching agent, desulfurizer, and dechlorinator. Sodium sulfite inhibits hepatocyte proliferation, promotes hepatocyte apoptosis and necrosis, and impairs mitochondrial integrity. Sodium sulfite induces superoxide anion production, primes neutrophils for enhanced superoxide anion generation, and induces neutrophil gene expression. Sodium sulfite can be used in studies related to pulmonary inflammation and gastric tissue injury .
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Cat. No.: HY-135152
CAS No.: 934182-09-9
Purity:  ≥99.0%
Research Areas:  

Cancer

CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor?activity .
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Cat. No.: HY-N3518
CAS No.: 193483-95-3
Mulberroside F is one of the main bioactive constituents in mulberry (Morus alba L.) . Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation. Mulberroside F also exhibits superoxide scavenging activity that is involved in the protection against auto-oxidation .
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Cat. No.: HY-130017
Purity:  98.68%
HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .
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Cat. No.: HY-P4666
CAS No.: 13589-07-6
Research Areas:  

Others

Valylhistidine is a dipeptide composed of valine and histidine (Val-His). Valylhistidine can form a dipeptide complex with Cu (II) that mimics superoxide dismutase but lacks activity .
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Cat. No.: HY-N2100
CAS No.: 115713-06-9
6'-O-beta-D-Glucosylgentiopicroside is a secoiridoid isolated from the roots of G. straminea. 6'-O-beta-D-Glucosylgentiopicroside strongly suppresses N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide generation .
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Cat. No.: HY-W196368
CAS No.: 2217-60-9
Thymohydroquinone is a COX-2 inhibitor and anti-SARS-CoV-2 agent that induces cytotoxicity, antiproliferative effects and inhibits tumor growth. Thymohydroquinone cannot scavenge superoxide radicals via σ (hydrogen atom transfer) and π-π attacks with superoxide anions. Thymohydroquinone can be used in research related to squamous cell carcinoma, fibrosarcoma and coronavirus disease 2019 (SARS-CoV-2 infection) .
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Cat. No.: HY-132132
CAS No.: 1234707-32-4
Target:  

Elastase

Research Areas:  

Inflammation/Immunology

Neutrophil elastase inhibitor 3 (compound 13), a benzoxazinone analog, shows effects on superoxide anion generation and exhibits as a neutrophil elastase (NE) inhibitor, with an IC50 of 80.8 nM for NE release .
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Cat. No.: HY-136651
CAS No.: 685119-25-9
Purity:  99.68%
Research Areas:  

Inflammation/Immunology

BNTA, a potent extracellular matrix (ECM) modulator, facilitates cartilage structural molecule synthesis on chondrocytes by activating superoxide dismutase 3 (SOD3). BNTA shows a promising potential for osteoarthritis alleviation by modulating cartilage generation .
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Cat. No.: HY-N1579R
CAS No.: 87-66-1
Pyrogallol (Standard) is the analytical standard of Pyrogallol. This product is intended for research and analytical applications. Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.
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Cat. No.: HY-120976
CAS No.: 157230-67-6
Purity:  99.84%
Research Areas:  

Others

DEPMPO is a phosphorus-substituted nitrone spin trap probe that can capture superoxide anions and hydroxyl radicals. DEPMPO forms stable spin adducts with hydroxyl, aryl, sulfite and superoxide radicals, and the formation of these adducts can be inhibited by catalase or superoxide dismutase. DEPMPO is rapidly absorbed after intraperitoneal injection and distributes uniformly in the liver, heart and blood of mice. DEPMPO can be used in studies related to oxygen radical detection .
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Cat. No.: HY-N10450
CAS No.: 72755-19-2
Synonyms: 1-Ethoxycarbonyl-β-carboline
Kumujian A (1-Ethoxycarbonyl-β-carboline), an anti-inflammatory agent, inhibits both superoxide anion generation (IC50 = 4.87 μg/mL) and elastase release (IC50 = 6.29 μg/mL) .
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Cat. No.: HY-N4096
CAS No.: 174391-64-1
Tsugaric acid A can significantly inhibit superoxide anion formation. Tsugaric acid A also protects human keratinocytes against damage induced by ultraviolet B (UV B) light. Tsugaric acid A can protect keratinocytes from photodamage.
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Cat. No.: HY-N3388
CAS No.: 66056-30-2
Licoisoflavone B is an orally active flavonoid found in licorice. Licoisoflavone B alleviates psoriasis via SCD1-targeted lipid metabolism reprogramming and suppression of Th17/IL-17-mediated inflammation. Licoisoflavone B inhiibits superoxide anion generation and superoxide anion-induced lipid peroxidation. Licoisoflavone B binds tightly to Lassa virus nucleoprotein and can be used as a nucleoprotein antagonist of Lassa virus. Licoisoflavone B exhibits anti-mutagenic activity
against carcinogenic mutagen, by preventing DNA damage. Licoisoflavone B can be used for the research of psoriasis, Lassa fever, inflammation and cancer .
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Cat. No.: HY-E70377
Synonyms: Cu/Zn SOD
Target:  

SOD

Research Areas:  

Inflammation/Immunology Cancer

Cu/Zn Superoxide dismutase (Cu/Zn SOD; SOD1) is a cytosolic copper-zinc dimer form of superoxide dismutase enzyme. Cu/Zn Superoxide dismutase has oxygen radical enzymatic dismutation .
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Cat. No.: HY-118824
CAS No.: 193224-22-5
Moschamine acts as an inhibitor of excessive superoxide production in mitochondria.
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Cat. No.: HY-150175
CAS No.: 1786411-17-3
HKSOX-1 is a fluorescent probe for the detection and imaging of superoxide anion radicals (O2 •−) with selectivity. HKSOX-1 reacts with superoxide anion radicals, cleaving the aryl triflate group to generate a free phenol and produce turn-on fluorescence. Derivative variants of HKSOX-1 include HKSOX-1r and HKSOX-1m. HKSOX-1 is applicable to studies related to endogenous superoxide detection .
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Cat. No.: HY-132829
CAS No.: 2248030-85-3
Synonyms: GC4711
Research Areas:  

Cancer

Rucosopasem manganese (GC4711) is a selective superoxide dismutase mimetic that converts superoxide to hydrogen peroxide. Rucosopasem manganese can be used for the research of cancer .
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