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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1307 Results for "
mtDNA content
" in MedChemExpress (MCE) Product Catalog:
Products (1307)
1307 Results for "mtDNA content" in MCE Product Catalog:
146
146 Publications Verification
Synonyms: SQ23377
Category:
Infection Antibiotics Microorganism Disease Research Anticancer Disease Research Fields Other Antibiotics
Target:
The product specifications provided below refer solely to the active content of Ionomycin.
114
114 Cited Publications
Cat. No.: HY-P0035A
CAS No.: 11061-68-0
Target:
Research Areas:
Insulin solution (human) is a polypeptide hormone that regulates the level of glucose. Insulin solution (human) can be used for the diabetes mellitus .
The product specifications provided below refer solely to the active content of Insulin (human).
The product specifications provided below refer solely to the active content of Insulin (human).
107
107 Cited Publications
Cat. No.: HY-N0322A
Category:
Target:
(Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
76
76 Cited Publications
Cat. No.: HY-P9907
CAS No.: 180288-69-1
Synonyms: Anti-Human HER2, Humanized Antibody
Research Areas:
Trastuzumab is a humanized IgG1 monoclonal antibody that selectively binds to HER2 with high affinity. Trastuzumab can be used for the research of HER2-positive metastatic breast cancer and gastric cancer . (Note: The product specifications below only indicate the effective content of Trastuzumab. The component ratio of this product is Trastuzumab : excipients = 1:0.6-1:0.9.)
75
75 Cited Publications
Synonyms: DL-Lactic acid sodium; E-270 sodium
Research Areas:
Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative .
This product has a content (w/w) of 60%, and 1 mL of the system contains 798 mg of Lactic acid sodium, i.e., a concentration of 798 mg/mL (i.e., 7.12 M).
The product specifications provided below indicate the total amount only; they do not represent the actual content of Lactic acid sodium.
This product has a content (w/w) of 60%, and 1 mL of the system contains 798 mg of Lactic acid sodium, i.e., a concentration of 798 mg/mL (i.e., 7.12 M).
The product specifications provided below indicate the total amount only; they do not represent the actual content of Lactic acid sodium.
53
Ammonium lactate (60%w/w in water) ((±)-Ammonium lactate) is the ammonium salt of lactic acid, with mild anti-bacterial properties. Ammonium lactate (60%w/w in water) can be used for the research of xerosis .
The product specifications provided below indicate the total amount only; they do not represent the actual content of Ammonium lactate.
The product specifications provided below indicate the total amount only; they do not represent the actual content of Ammonium lactate.
38
38 Cited Publications
Cat. No.: HY-D1913
28
28 Cited Publications
Cat. No.: HY-N6785
CAS No.: 78111-17-8
Target:
The product specifications provided below refer solely to the active content of Okadaic acid.
25
25 Cited Publications
Target:
Research Areas:
ML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 μM) with anti-proliferative activity, which direct binds to USP2 (Kd=5.2 μM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP .
25
25 Cited Publications
Synonyms: bisBenzimide H 33258; H 33258
20
Target:
Research Areas:
Azoxymethane (AOM) is a colon carcinogen which leads to the formation of DNA adducts. Azomethane is a procarcinogen that requires metabolic activation via cytochrome P450 (P450) enzymes (primarily CYP2E1) .
The product specifications provided below refer solely to the active content of Azoxymethane.
The product specifications provided below refer solely to the active content of Azoxymethane.
18
18 Cited Publications
Synonyms: 9,11-Methanoepoxy PGH2
Target:
Research Areas:
U-46619 (9,11-Methanoepoxy PGH2) is a stable analogue of Thromboxane A2 (HY-113350) (TXA2) and acts as a potent TXA2 (TP) agonist. U-46619 also is a RhoA agonist. U-46619 stimulates the activation of RhoA through TXA2 receptor activation .
The product specifications provided below refer solely to the active content of U-46619.
The product specifications provided below refer solely to the active content of U-46619.
16
Category:
Macrolide Antibiotics Antibiotics Animal Marine natural products Other Diseases Sponge Disease Research Anticancer Disease Research Fields
Target:
The product specifications provided below refer solely to the active content of Latrunculin A.
15
Target:
Research Areas:
Methylnitronitrosoguanidine (MNNG) is an orally active alkylating agent with toxic and mutagenic effects. Methylnitronitrosoguanidine can as a carcinogen and mutagen . 50% water content, specifications are based on dry weight.
15
Research Areas:
Lonafarnib (Sch66336) is an orally active, blood-brain barrier penetrant farnesyltransferase (FPTase) inhibitor. Lonafarnib increases the phosphorylation levels of Akt, CaMKII and CREB, upregulates BDNF expression in the hippocampus, elevates the content of α7nAChR on cell membranes, and blocks the isoprenylation of H-Ras. Lonafarnib repairs synapses and reverses spatial memory deficits in Aβ1-42 model mice. Lonafarnib inhibits RSV fusion and replication, and alleviates virus-induced lung injury. Lonafarnib activates the lysosomal and autophagic pathways, and reduces the phosphorylation and aggregation of tau. Lonafarnib acts synergistically with Sorafenib (HY-10201) to promote apoptosis, and inhibits the proliferation and invasion of melanoma cells. Lonafarnib inhibits the farnesylation of progerin, repairs nuclear membrane defects, and activates the cGAS-STING-STAT1 signaling pathway. Lonafarnib can be used in research related to diseases including Alzheimer's disease, viral infections, melanoma, and progeria .
14
14 Cited Publications
Vacuolin-1 is a potent and cell-permeable lysosomal exocytosis inhibitor. Vacuolin-1 blocks the Ca 2+-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation. Vacuolin-1 can induce vacuole formation and increase the percentage of enucleated cells .
13
13 Cited Publications
Cat. No.: HY-B0608
CAS No.: 18472-51-0
Target:
Research Areas:
Chlorhexidine digluconate (20% in water) is a orally active cationic antimicrobial agent that targets microbial cell membranes. Chlorhexidine digluconate (20% in water) binds to cell membrane phospholipids non-specifically, destroys membrane structure and induces leakage of cell contents. Chlorhexidine digluconate (20% in water) has broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria. Chlorhexidine digluconate (20% in water) can interfere with membrane permeability, cause protein precipitation and energy metabolism disorders, such as rapid inhibition of microbial growth and induction of cell death (necrosis or apoptosis) .
The product specifications provided below refer solely to the active content of Chlorhexidine digluconate.
The product specifications provided below refer solely to the active content of Chlorhexidine digluconate.
12
12 Cited Publications
Cat. No.: HY-101883A
Target:
Research Areas:
BCECF Acetoxymethyl ester is a cell membrane permeable compound widely-used as a fluorescent indicator for intracellular pH. BCECF Acetoxymethyl ester could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm .
The product specifications provided below refer solely to the active content of BCECF Acetoxymethyl ester.
The product specifications provided below refer solely to the active content of BCECF Acetoxymethyl ester.
12
12 Cited Publications
Synonyms: Chuanxiongzine; Tetramethylpyrazine
12
12 Cited Publications
Cat. No.: HY-N0935
CAS No.: 76494-51-4
Synonyms: Chuanxiongzine hydrochloride; Tetramethylpyrazine hydrochloride
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
