22 Results for "

oleanane-type triterpenoid

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "oleanane-type triterpenoid" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N0819
CAS No.: 89412-79-3
Raddeanin A is an oleanane-type triterpenoid saponin with oral activity. Raddeanin A inhibits SRC, mTOR, JNK, VEGFR2, NLRP3 inflammasome, Wnt/β-catenin, Wee1, PI3K/AKT signaling pathway, MAPK/ERK signaling pathway, AR-FL, AR-Vs, and downregulates the expression of p-PI3K and p-AKT. Raddeanin A inhibits osteoclast formation, bone resorption, osteolysis, cancer cell invasion, migration, proliferation, angiogenesis and epithelial-mesenchymal transition, while induces apoptosis, cell cycle arrest, ROS production, immunogenic cell death and dendritic cell maturation. Raddeanin A improves blood-retinal barrier function, alleviates inflammation, regulates the tumor microenvironment, and enhances the activity of anti-PD-1 antibody. Raddeanin A is applicable to the research of breast cancer-associated osteolysis, human osteosarcoma, colorectal cancer, glioblastoma, Alzheimer's disease, cholangiocarcinoma, melanoma, non-small cell lung cancer, castration-resistant prostate cancer and multiple myeloma .
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1 Cited Publications
Cat. No.: HY-N7026
CAS No.: 1807732-38-2
Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice .
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Cat. No.: HY-N8156
CAS No.: 595-14-2
Soyasapogenol C is an oleanane-type triterpenoid. Soyasapogenol C exhibits anti-HSV-1 activity, with an IC50 of 18.9 μM .
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Cat. No.: HY-N8609
CAS No.: 1262326-46-4
Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch .
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Cat. No.: HY-N11068
CAS No.: 96315-52-5
Huzhangoside C is a oleanane-type triterpenoid saponin that can be isolated from the roots of Clematis argentilucida .
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Cat. No.: HY-N13847
CAS No.: 105038-43-5
Uralsaponin B is classified as an oleanane-type triterpenoid saponin. Uralsaponin B exhibits potential anti-inflammatory and anti-infective activities.
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Cat. No.: HY-N3523
CAS No.: 38337-25-6
3-O-Beta-D-Glucopyranosylplatycodigenin is an oleanane-type triterpenoid isolated from roots of Platycodon grandiflorum. 3-O-Beta-D-Glucopyranosylplatycodigenin exhibits anti-proliferative activities against HSC-T6 cell line with an IC50 of 13.36 μM .
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Cat. No.: HY-N13115
CAS No.: 35931-54-5
Synonyms: (Z)-Protoescigenin 21-tiglate
21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively .
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Cat. No.: HY-N13115A
CAS No.: 7047-43-0
Synonyms: (E)-21-Angeloyl-protoaescigenin
Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively .
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Cat. No.: HY-N19898
CAS No.: 1215281-16-5
Raddeanoside R22 is an oleanane-type triterpenoid bisdesmoside saponin found in the rhizome and roots of Anemone raddeana Regel .
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Cat. No.: HY-N19813
CAS No.: 1807855-01-1
Flaccidoside VI is an inhibitor of nitric oxide production belonging to oleanane-type triterpenoid saponins. Flaccidoside VI can be isolated from the rhizomes of Anemone flaccida. Flaccidoside VI exhibits significant inhibitory activity against lipopolysaccharide-induced nitric oxide production .
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Cat. No.: HY-N19794
CAS No.: 1965272-21-2
Derrisaponin A is an oleanane-type triterpenoid saponin and sweetener found in the stems of Derris eriocarpa, with sweetness intensity approximately 80 times that of Sucrose (HY-B1779) at 1% concentration. Derrisaponin A shows no acute toxic activity. Derrisaponin A can be used for research on hypertension, hyperglycemia, and obesity .
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Cat. No.: HY-N19793
CAS No.: 1965272-23-4
Derrisaponin B is an oleanane-type triterpenoid saponin and sweetener found in the stems of Derris eriocarpa How, with sweetness intensity approximately 2 times that of Sucrose (HY-B1779) at 1% concentration. Derrisaponin B exhibits sweet taste activity. Derrisaponin B can be used for research on hypertension, hyperglycemia, and obesity .
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Cat. No.: HY-N19857
CAS No.: 562070-88-6
Millettiasaponin A is an oleanane-type triterpenoid saponin found in the stems of Derris eriocarpa and roots of Millettia speciosa. Millettiasaponin A is 150 times sweeter than Sucrose (HY-B1779) at 1% concentration. Millettiasaponin A can be used in research on hypertension and obesity. .
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Cat. No.: HY-N0819R
CAS No.: 89412-79-3
Raddeanin A (Standard) is the analytical standard of Raddeanin A (HY-N0819). This product is intended for research and analytical applications. Raddeanin A is an oleanane-type triterpenoid saponin with oral activity. Raddeanin A inhibits SRC, mTOR, JNK, VEGFR2, NLRP3 inflammasome, Wnt/β-catenin, Wee1, PI3K/AKT signaling pathway, MAPK/ERK signaling pathway, AR-FL, AR-Vs, and downregulates the expression of p-PI3K and p-AKT. Raddeanin A inhibits osteoclast formation, bone resorption, osteolysis, cancer cell invasion, migration, proliferation, angiogenesis and epithelial-mesenchymal transition, while induces apoptosis, cell cycle arrest, ROS production, immunogenic cell death and dendritic cell maturation. Raddeanin A improves blood-retinal barrier function, alleviates inflammation, regulates the tumor microenvironment, and enhances the activity of anti-PD-1 antibody. Raddeanin A is applicable to the research of breast cancer-associated osteolysis, human osteosarcoma, colorectal cancer, glioblastoma, Alzheimer's disease, cholangiocarcinoma, melanoma, non-small cell lung cancer, castration-resistant prostate cancer and multiple myeloma.
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Cat. No.: HY-N17961
CAS No.: 843668-13-3
Synonyms: Septemloside I
Kalopanaxsaponin I (Septemloside I) is an oleanane-type triterpenoid that exists in the fruits of Stauntonia brachyanthera. Kalopanaxsaponin I inhibits LPS (HY-D1056)-induced nitric oxide production in macrophages, with a IC50 of 80.25 μM .
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Cat. No.: HY-N19757
CAS No.: 112667-17-1
3-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl) echinocystic acid is an oleanane-type triterpenoid saponin. 3-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl) echinocystic acid acts as a dermatophyte growth inhibitor with a MIC range of 6.25-25 μg/mL. 3-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl) echinocystic acid can be used in the research of dermatophyte infections, bacterial infections and yeast infections .
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Cat. No.: HY-N17752
CAS No.: 1453187-72-8
Phaseoloideside C is an oleanane-type triterpenoid saponin. Phaseoloideside C can be isolated from the seeds of *Entada phaseoloides*. Phaseoloideside C exhibits no cytotoxicity against hepatocellular carcinoma cells, esophageal carcinoma cells, cervical carcinoma cells, and colon carcinoma cells .
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Cat. No.: HY-E71272
Research Areas:  

Others

β-Amyrin 28-monooxygenase (EC 1.14.13.201), found in plants, is involved in the biosynthesis of oleanane-type triterpenoids, such as ginsenoside Ro. The enzyme from Medicago trunculata (CYP716A12) can also convert α-amyrin and lupeol to ursolic acid and betulinic acid, respectively.
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Cat. No.: HY-N9826
CAS No.: 561-47-7
Icterogenin is a selective inhibitor targeting the Bcl-XL/Bak BH3 domain peptide interaction and exhibits anti-leukemic activity. Icterogenin regulates protein interactions and affects tumor cell survival. Icterogenin is an oleanane-type triterpenoid compound that can be isolated from Lantana camara and is useful in the field of anti-tumor drug development .
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