Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Related Products (2569)
Related Products (2569)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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5-Phenylthieno[2,3-d]pyrimidin-4-amine
![5-Phenylthieno[2,3-d]pyrimidin-4-amine](https://file.medchemexpress.com/product_pic/hy-w079315.gif "Click to View 5-Phenylthieno[2,3-d]pyrimidin-4-amine Product Detail")
0 ImagesCat. No.: HY-W079315CAS No.: 195193-10-35-Phenylthieno[2,3-d]pyrimidin-4-amine (Compound 3b) is a heterocyclic compound with antiviral and antiprotozoal activities.
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Carbazomycin D
0 ImagesCat. No.: HY-N12232CAS No.: 108073-63-8Carbazomycin D exhibits antituberculosis and antimalarial activities, that inhibits Plasmodium falciparum with an IC50 > 10 μg/mL, inhibits Mycobacterium tuberculosis with MIC of 25 μg/mL. Carbazomycin D exhibits cytotoxicity in cell MCF-7, KB, NCI-H187 and Vero, with IC50s of 21.3, 33.2, 12.9, and 34.3 μg/mL, respectively.
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SN00799639
0 ImagesCat. No.: HY-184373CAS No.: 1340790-22-8Synonyms: SN639SN00799639 (SN639) is an inhibitor of Haemonchus contortus. SN00799639 inhibits the motility of exsheathed third-stage larvae of Haemonchus contortus with an IC50 of 8.4 μM. SN00799639 inhibits the development of exsheathed third-stage larvae of Haemonchus contortus into fourth-stage larvae with an IC50 of 0.29 μM. SN00799639 shows no significant cytotoxicity against human mammary epithelial cells. SN00799639 can be used for research on Haemonchus contortus infection.
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Kijimicin sodium
0 ImagesCat. No.: HY-123444ACAS No.: 129388-64-3Kijimicin sodium is a polyether ionophore antibiotic originally discovered in Actinomadura sp. MI215-NF3. Kijimicin sodium inhibits HIV-1 replication and reduces the infectivity of progeny viral particles. Kijimicin sodium exhibits inhibitory activity against intracellular T. gondii (IC50 = 45.6 nM), extracellular parasites (IC50 = 216.6 pM) and C. parvum (IC50 = 7.7 nM), and controls acute T. gondii infection in mice. Kijimicin sodium can be used for research on HIV, toxoplasmosis, cryptosporidiosis, and bacterial infections.
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3-Butylidenephthalide (Standard)
0 Images3-Butylidenephthalide (Standard) is the analytical standard of 3-Butylidenephthalide. This product is intended for research and analytical applications. 3-Butylidenephthalide (Butylidenephthalide) is a phthalic anhydride derivative identified in Ligusticum chuanxiong Hort, and has larvicidal activity (LC50 of 1.56 mg/g for Spodoptera litura larvae).
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Atovaquone (Standard)
0 ImagesSynonyms: Atavaquone (Standard)Atovaquone (Standard) is the analytical standard of Atovaquone. This product is intended for research and analytical applications. Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasite’s mitochondrial cytochrome bc1 complex. Atovaquone is against human and P. falciparum cytochrome bc1 activity with IC50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia.
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SET-12
0 ImagesCat. No.: HY-179710CAS No.: 2241572-39-2SET-12 is an antiparasitic agent with high activity and selectivity against the Leishmania amazonensis. SET-12 exhibits excellent activity against the pre-flagellated form of the Leishmania amazonensis, with an IC₅₀ of 10.89 μM and a selectivity index (SI) of up to 12.1. SET-12 is also effective against the non-flagellated form within cells, with an IC₅₀ of 3.81 μM and a further increased selectivity index (SI) to 34.5. SET-12 causes signs of parasite cell apoptosis, including mitochondrial damage and accumulation of ROS.
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Eprinomectin B1b
0 ImagesCat. No.: HY-N8484CAS No.: 133305-89-2Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.
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5,6-Dihydroxyindole (Standard)
0 ImagesCat. No.: HY-W018025RCAS No.: 3131-52-05,6-Dihydroxyindole (Standard) is the analytical standard of 5,6-Dihydroxyindole. This product is intended for research and analytical applications. 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens.
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Antimalarial agent 50
0 ImagesCat. No.: HY-174325CAS No.: 2384242-67-3Antimalarial agent 50 is an antiplasmodial compound. Antimalarial agent 50 has an effect against Plasmodium berghei induced malaria infection in mice model. Antimalarial agent 50 can regulate oxidative stress and significantly reduce the levels of inflammatory factors. Antimalarial agent 50 can be used for the research of the malaria.
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Cordysinin C/D
0 ImagesCat. No.: HY-N13288CAS No.: 148683-93-6Cordysinin C/D (compound 9) is a potential anti-plasmodial compound that can effectively inhibit Plasmodium falciparum 3D7 strain.
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Eilatin
0 ImagesCat. No.: HY-183242CAS No.: 120154-96-3Eilatin is a seven-ring pyridoacridine marine alkaloid with anticancer, antibacterial, and antiparasitic activities. Eilatin acts as a DNA intercalator with selectivity for electron-deficient polycyclic purines; it can chelate Ni2+ ions and cleave DNA via hydroxyl radical generation. Eilatin induces the SOS response in bacteria, inhibits cancer cell proliferation, and induces cancer cell differentiation and reversion of transformation. The IC50 of Eilatin against Trypanosoma brucei brucei is 1.33 μM. Eilatin can be used in research related to colon tumors, neuroblastoma, chronic myeloid leukemia, acute myeloid leukemia, and trypanosome infections.
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Ganaplacide hydrochloride (Standard)
0 ImagesCat. No.: HY-108024ARCAS No.: 2751586-94-2Synonyms: KAF156 hydrochloride (Standard); GNF156 hydrochloride (Standard)Ganaplacide hydrochloride (Standard) is the analytical standard of Ganaplacide (hydrochloride) (HY-108024A). This product is intended for research and analytical applications. Ganaplacide (KAF156) hydrochloride is a first-in-class, orally active imidazolopiperazine antimalarial agent. Ganaplacide hydrochloride is active against a broad range of Plasmodium species, including drug-resistant parasites. Ganaplacide hydrochloride is parasiticidal against both asexual and sexual blood stages as well as the liver stages of the parasite.
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Antiparasitic agent-35
0 ImagesCat. No.: HY-180361CAS No.: 13851-60-0Antiparasitic agent-35 (table 2 n = 5 R = Me) is an antiparasitic agent. Antiparasitic agent-35 shows schistosomicidal effccts.
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Chinifur
0 ImagesSynonyms: QuinifurylChinifur (Quinifuryl), a Nitrofuran derivative, is a selective inhibitor of trypanothione reductase and also a radical-generating substrate for trypanothione reductase (Ki = 4.5 μM).
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Antiparasitic agent-46
0 ImagesCat. No.: HY-184085CAS No.: 100967-19-9Antiparasitic agent-46 is a p-aminophenoxypropyl-based monoamine and a structural analog of Antiparasitic agent-45 (HY-184084). Antiparasitic agent-46 shows no activity against Schistosoma mansoni in mice and exhibits extremely strong acute oral toxicity. Antiparasitic agent-46 can be used in studies related to schistosome infection.
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DHFR-IN-20
0 ImagesCat. No.: HY-168069DHFR-IN-20 (Compound LA1) is a Plasmodium falciparum dihydrofolate reductase (DHFR) inhibitor, with Kis of 0.16, 0.30, 6.6 nM for PfDHFR-WT, PfDHFR-QM, HsDHFR. DHFR-IN-20 has antimalarial activities (IC50: 1.4 nM and 1.6 μM for P. falciparum carrying the wild-type (TM4/8.2) and the quadruple mutant (V1/S) PfDHFR enzyme.
