2. PI3K/Akt/mTOR TGF-beta/Smad Stem Cell/Wnt Cell Cycle/DNA Damage
  3. Akt PKA CDK
  4. Akt1&PKA-IN-1

Akt1&PKA-IN-1 is a potent dual Akt/PKA inhibitor with IC50 values of 0.03 , 0.11 μM, and 9.8 μM for PKAa, Akt, and CDK2, respectively. Akt1&PKA-IN-1 is selective for cyclin-dependent kinase 2 (CDK2).

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Akt1&PKA-IN-1

Akt1&PKA-IN-1 Estructura química

No. CAS : 1334107-58-2

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Other Forms of Akt1&PKA-IN-1:

Akt1&PKA-IN-1 Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas Akt:

Ver todas las isoformas
Akt Akt1 Akt2 Akt3

Ver todos los productos específicos de isoformas PKA:

Ver todas las isoformas
PKA PKAR PKACα

Ver todos los productos específicos de isoformas CDK:

Ver todas las isoformas
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85 CDK10 CDK15 CDK17 CDK18 CDK20 PITSLRE

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Descripciòn

Akt1&PKA-IN-1 is a potent dual Akt/PKA inhibitor with IC50 values of 0.03 , 0.11 μM, and 9.8 μM for PKAa, Akt, and CDK2, respectively. Akt1&PKA-IN-1 is selective for cyclin-dependent kinase 2 (CDK2)[1].

IC50 & Target[1]

PKAa

0.03 μM (IC50)

Akt

0.11 μM (IC50)

CDK2

9.8 μM (IC50)

Peso molecular

386.27

Fòrmula

C20H17Cl2N3O
No. CAS
SMILES

O=C(C1=CC2=C(C=NC=C2)C=C1)N[C@@H](C3CNC3)C4=CC(Cl)=C(C=C4)Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Akt1&PKA-IN-1 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Akt1&PKA-IN-11334107-58-2AktPKACDKPKBProtein kinase BProtein kinase ACyclin dependent kinaseInhibitorinhibitorinhibit

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Nombre del producto:
Akt1&PKA-IN-1
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HY-148868
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