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Art. -Nr.: HY-114338B

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Dalpiciclib isethionate

(Synonyms: SHR-6390 isethionate)

1 Cited Publications

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Dalpiciclib (isethionate) is a CDK4/6 inhibitor. Dalpiciclib (isethionate) inhibits the kinase activity of CDK4 and CDK6, thereby blocking the G1-to-S phase transition of the cell cycle and suppressing abnormal cell proliferation. Dalpiciclib (isethionate) can be used for the study of breast cancer.

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CAS. Nr.: 1980822-14-7
Formel: C₂₇H₃₆N₆O₆S
Molecular Weight:572.68

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Dalpiciclib isethionate Chemical Structure

CAS. Nr.: 1980822-14-7

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Beschreibung

IC₅₀ & Target^[1]

CDK4

CDK6

Alle CDK Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 1980822-14-7
Molecular Weight 572.68
Formel C₂₇H₃₆N₆O₆S
SMILES

O=C1C(C(C)=O)=C(C)C2=C(N1C3CCCC3)N=C(NC4=NC=C(C5CCNCC5)C=C4)N=C2.O=S(O)(CCO)=O
Synonyms

SHR-6390 isethionate
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Leuk Res Rep

2025 Dec 20.

Reinheit & Dokumentation

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. ZHU Xiaoyu, et al. Use of Composition Containing CDK4/6 Inhibitor in Combination with Anastrozole in Preparation of Medicament for Treating Tumor Diseases. WO2020/156446 A1. World Intellectual Property Organization (WIPO). August 6, 2020.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Dalpiciclib isethionate

1 Cited Publications

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Dalpiciclib isethionate

Publications Citing Use of MedChemExpress (MCE) Dalpiciclib isethionate

Alle CDK Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (1)

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Dalpiciclib isethionate Related Classifications

HY-114338B Related Classifications