ATM Inhibitor-4
ATM Inhibitor-4 (compound 39) is a potent and selective ATM inhibitor, with an IC50 of 0.32 nM. ATM Inhibitor-4 shows stronger inhibition of PI3K kinases family. ATM Inhibitor-4 shows a full inhibition of mTOR at 1 μM. ATM Inhibitor-4 exhibits favorable metabolic stability.
For research use only. We do not sell to patients.
- CAS No.: 2769140-74-9
- Formula: C26H29FN6O3
- Molecular Weight:492.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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ATM 0.32 nM (IC50) |
PI3K |
mTOR |
Chemical Information
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CAS No. 2769140-74-9
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Molecular Weight 492.55
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Formula C26H29FN6O3
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SMILES
COCCN1C(N(C2=C1C3=CC(C4=CC=C(C=C4)NC(NCCN5CC(C5)F)=O)=CC=C3N=C2)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)