1. Cell Cycle/DNA Damage
  2. CDK
  3. BML-259


Cat. No.: HY-108348 Purity: 98.78%
COA Handling Instructions

BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC50s of 64 and 98 nM for Cdk5 and Cdk2, respectively.

For research use only. We do not sell to patients.

BML-259 Chemical Structure

BML-259 Chemical Structure

CAS No. : 267654-00-2

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 61 In-stock
10 mM * 1 mL in DMSO USD 61 In-stock
5 mg USD 55 In-stock
10 mg USD 96 In-stock
25 mg USD 210 In-stock
50 mg USD 365 In-stock
100 mg USD 620 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


BML-259 is a potent cyclin-dependent kinase 5 (Cdk5) inhibitor, with IC50s of 64 and 98 nM for Cdk5 and Cdk2, respectively[1].

In Vitro

BML-259 (10 μM) protects large population of cells against non-Aβ component of Alzheimer's disease amyloid (NAC)-evoked cell death[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight







White to off-white




Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (480.12 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8410 mL 19.2049 mL 38.4098 mL
5 mM 0.7682 mL 3.8410 mL 7.6820 mL
10 mM 0.3841 mL 1.9205 mL 3.8410 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
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BML-259 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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