14-Norpseurotin A
14-Norpseurotin A (14-Norpseurotin) is an Antibacterial, antimalarial, and anticancer agent. 14-Norpseurotin A is isolated from various fungi of the Aspergillus genus. 14-Norpseurotin A induces neurite outgrowth. 14-Norpseurotin A inhibits the growth of Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus. 14-Norpseurotin A exhibits antileishmanial activity against L. donovani, antiplasmodial activity against P. falciparum, and shows no activity against T. cruzi. 14-Norpseurotin A exerts anticancer activity against breast cancer. 14-Norpseurotin A is used in research related to leishmaniasis, malaria, and breast cancer.
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- CAS No.: 1031727-34-0
- Formule: C21H23NO8
- Masse moléculaire:417.41
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
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Fungal Metabolite |
Leishmania |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
41 μM
Compound: 4
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Cytotoxicity against human K562 cells after 48 hrs by MTT assay
Cytotoxicity against human K562 cells after 48 hrs by MTT assay
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[PMID: 19256529] |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1031727-34-0
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Masse moléculaire 417.41
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Formule C21H23NO8
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SMILES
O=C(N1)[C@@](OC([C@@H](O)[C@@H](O)/C=C\C)=C2C)(C2=O)[C@@H](O)[C@]1(OC)C(C3=CC=CC=C3)=O
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Synonyms
14-Norpseurotin
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Ge HM, et al. Bioactive alkaloids from endophytic Aspergillus fumigatus. Journal of natural products. 2009 Apr;72(4):753-5. [Content Brief]
[3]. Zhang M, et al. Cytotoxic alkaloids and antibiotic nordammarane triterpenoids from the marine-derived fungus Aspergillus sydowi. Journal of natural products. 2008 Jun;71(6):985-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
14-Norpseurotin A Related Classifications
HY-133101 Related Classifications
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