DNMT/HDAC-IN-2
DNMT/HDAC-IN-2 (Compound Y7) is a DNMT and HDAC inhibitor with IC50 values for DNMT1, HDAC1, and HDAC6 of 365, 0.2, and 8.91 nM respectively. DNMT/HDAC-IN-2 inhibits the proliferation of breast cancer cells. DNMT/HDAC-IN-2 significantly reduces tumor growth in xenografts and transgenic breast cancer mouse models. DNMT/HDAC-IN-2 can be used for the study of breast cancer.
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- CAS No.: 2548725-57-9
- Formule: C28H38N4O5
- Masse moléculaire:510.63
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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HDAC1 0.2 nM (IC50) |
HDAC6 8.91 nM (IC50) |
DNMT1 365 nM (IC50) |
Chemical Information
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CAS No. 2548725-57-9
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Masse moléculaire 510.63
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Formule C28H38N4O5
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SMILES
COC1=C(C=C(C2=C1)N=C(C=C2NC3CCN(CC3)C)C4=CC=C(O4)C)OCCCCCCC(NO)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DNMT/HDAC-IN-2 Related Classifications
HY-175988 Related Classifications
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