LQFM030
LQFM030 is a novel small molecule MDM2 inhibitor. LQFM030 exhibits concentration dependent cytotoxicity in K562 cells (IC50 = 0.28 mM). LQFM030 induces cell apoptosis through G0/G1 phase cell cycle arrest and increased Caspase activity. LQFM030 downregulates the mRNA expression of MDM2, MDMX, p73, MYC, and NF-κB. LQFM030 is commonly used in research on cancers such as leukemia.
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- CAS No.: 2180931-49-9
- Formule: C16H19ClN4O
- Masse moléculaire:318.80
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 2180931-49-9
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Masse moléculaire 318.80
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Formule C16H19ClN4O
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SMILES
CC(N1CCN(CC2=CN(C3=CC=C(Cl)C=C3)N=C2)CC1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)