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Cat. No.: HY-160941

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CDK2-IN-29

CDK2-IN-29 (Compound 13q) is an inhibitor for cyclin-dependent kinase (CDK), with IC₅₀ of 96 nM and 360 nM, for CDK 2 and CDK 4, respectively.

For research use only. We do not sell to patients.

CAS No.: 247149-58-2
Formula: C₂₄H₃₁N₅O₂
Molecular Weight:421.54

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

CDK2-IN-29 Chemical Structure

CAS No.: 247149-58-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

CDK2-IN-29 (Compound 13q) is an inhibitor for cyclin-dependent kinase (CDK), with IC₅₀ of 96 nM and 360 nM, for CDK 2 and CDK 4, respectively^[1].

IC₅₀ & Target

CDK2

96 nM (IC₅₀)

CDK4

360 nM (IC₅₀)

All CDK Isoforms :

Chemical Information

CAS No. 247149-58-2
Molecular Weight 421.54
Formula C₂₄H₃₁N₅O₂
SMILES

O=C1C2=C(C3=NNC(C4CCCCC4)=C13)C=CC=C2NC(CN5CCC(CC5)CN)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yue EW, et al., Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3(1,2). J Med Chem. 2002 Nov 21;45(24):5233-48. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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