CDK4-IN-6
CDK4-IN-6 is a CDK4 inhibitor with an IC50 of 0.0011 μM. CDK4-IN-6 can be used for the research of breast cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 3120500-44-6
- Formel: C20H29FN6O3S
- Molecular Weight:452.55
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
CDK4 0.0011 μM (IC50) |
In Vitro
Chemical Information
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CAS. Nr. 3120500-44-6
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Molecular Weight 452.55
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Formel C20H29FN6O3S
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SMILES
O[C@H](CN(S(=O)(C)=O)CC1)[C@@H]1NC2=NC=C3C(N([C@@H]4CCNC[C@@H]4F)C(C5CC5)=C3)=N2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)