CDK4-IN-7
CDK4-IN-7 is a CDK4 inhibitor with an IC50 of 26 nM. CDK4-IN-7 shows selectivity for CDK1, with an IC50 of 4.2262 μM. CDK4-IN-7 can be used in cancer research.
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- CAS. Nr.: 3113087-01-4
- Formel: C20H28F2N6O2S
- Molecular Weight:454.54
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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CDK4 26 nM (IC50) |
CDK1 4.2262 μM (IC50) |
CDK4-IN-7 (Compound 5) potently inhibits CDK4 with an IC50 of 26 nM and shows 162.5-fold selectivity for CDK4 over CDK1 in a biochemical kinase assay measuring retinoblastoma protein Ser780 phosphorylation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3113087-01-4
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Molecular Weight 454.54
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Formel C20H28F2N6O2S
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SMILES
CC1=CC2=CN=C(N[C@H]3[C@H](F)CN(S(C4CC4)(=O)=O)CC3)N=C2N1[C@@H]5CCNC[C@@H]5F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CDK4-IN-7 Related Classifications
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