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Cat. No.: HY-191296

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CDK9 ligand-11

CDK9 ligand-11 is a ligand for target protein for PROTAC targeting CDK9, and can be used to synthesize PROTAC CDK9 degrader-24 (HY-191295). CDK9 ligand-11 can be used for research on triple-negative breast cancer.

For research use only. We do not sell to patients.

CAS No.: 3031327-90-6
Formula: C₂₃H₃₄N₈O
Molecular Weight:438.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

CDK9 ligand-11 Chemical Structure

CAS No.: 3031327-90-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target

^[1]

CDK9

All CDK Isoforms :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Breast Cancer Modeling

Chemical Information

CAS No. 3031327-90-6
Molecular Weight 438.57
Formula C₂₃H₃₄N₈O
SMILES

CN1CCC(OC2=NC3=C(C(C)C)C=NN3C(NCC(C=CC(N)=C4)=C4N(C)C)=N2)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xiaohua Chen, et al. Degradation agents for cyclin dependent kinase, preparation method therefor, pharmaceutical composition thereof and use thereof. WO2020035049A1. WIPO 2020-02-20.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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CDK9 ligand-11

All CDK Isoforms

Biological Activity

Description

IC50 & Target

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CDK9 ligand-11 Related Classifications

HY-191296 Related Classifications

Bioz

Keywords

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