CDK7-IN-11
CDK7-IN-11 is an orally active CDK7 inhibitor. CDK7-IN-11 exhibits high CDK7 inhibitory activity with IC50 value of 4.2 nM. CDK7-IN-11 can be effectively used for the research of diseases associated with CDK7.
For research use only. We do not sell to patients.
- CAS No.: 2414896-32-3
- Formula: C26H28N6O2S
- Molecular Weight:488.60
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
CDK7 4.2 nM (IC50) |
CDK7-IN-11 (example 5) has inhibitory activity for CDK7 with IC50 value of 4.2 nM[1].
CDK7-IN-11 (72 h) inhibits cell proliferation in MDA-MB-468 cells and HepG2 cells with IC50 values of 14.0 nM and 3.0 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:MDA-MB-468 cells, HepG2 cells
-
Concentration:
-
Incubation Time:72 h
-
Result:Showed antiproliferative effect in cells.
Chemical Information
-
CAS No. 2414896-32-3
-
Molecular Weight 488.60
-
Formula C26H28N6O2S
-
SMILES
N#CC1=CC(C2=CC([C@H](C)C(NC3=NC=C(CC)S3)=O)=CC=C2)=CN=C1NC(/C=C/CN(C)C)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK7-IN-11 Related Classifications
HY-145655 Related Classifications
Powered by Bioz