CDK9 ligand 6
CDK9 ligand 6 is a PROTAC target protein ligand targeting CDK9, which can be used in research related to PROTAC synthesis, such as serving as the target protein ligand for PROTAC CDK9 degrader-13 (HY-184693).
For research use only. We do not sell to patients.
- Formula: C16H16Cl2N2O5
- Molecular Weight:387.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK9 |
CDK9 ligand 6 (compound 6c) serves as the target protein ligand for PROTAC CDK9 degrader-13 (HY-184693). PROTAC CDK9 degrader-13 is a selective CDK9 PROTAC degrader. It downregulates the anti-apoptotic protein Mcl-1, activates the Caspase-3 pathway, and induces apoptosis in acute myeloid leukemia cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 387.21
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Formula C16H16Cl2N2O5
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SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(COCC#C)=NC3=CC(Cl)=C(Cl)C=C23)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK9 ligand 6 Related Classifications
HY-184694 Related Classifications
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