CDK9 ligand 6
CDK9 ligand 6 is a PROTAC target protein ligand targeting CDK9, which can be used in research related to PROTAC synthesis, such as serving as the target protein ligand for PROTAC CDK9 degrader-13 (HY-184693).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C16H16Cl2N2O5
- 分子量:387.21
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
CDK9 |
体外実験
CDK9 ligand 6 (compound 6c) serves as the target protein ligand for PROTAC CDK9 degrader-13 (HY-184693). PROTAC CDK9 degrader-13 is a selective CDK9 PROTAC degrader. It downregulates the anti-apoptotic protein Mcl-1, activates the Caspase-3 pathway, and induces apoptosis in acute myeloid leukemia cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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分子量 387.21
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分子式 C16H16Cl2N2O5
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SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(COCC#C)=NC3=CC(Cl)=C(Cl)C=C23)O1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CDK9 ligand 6 関連分類
HY-184694 関連分類
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