CDK9 ligand-8
CDK9 ligand-8 is a carboxymethylene-modified analog of AT7519 (HY-50940) and a CDK9 ligand. CDK9 ligand-8 can serve as a target protein ligand for PROTAC synthesis-related research, such as AMC-3-221 (HY-189826).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2518236-42-3
- 分子式: C18H19Cl2N5O4
- 分子量:440.28
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
CDK9 |
体外実験
CDK9 ligand-8 (compound 17) can serve as the target protein ligand for AMC-3-221 (HY-189826), a CDK9 PROTAC degrader with a DC50 of 8 nM, which can be used in research related to acute myeloid leukemia[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2518236-42-3
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分子量 440.28
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分子式 C18H19Cl2N5O4
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SMILES
OC(CN1CCC(NC(C2=NNC=C2NC(C3=C(Cl)C=CC=C3Cl)=O)=O)CC1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CDK9 ligand-8 関連分類
HY-189827 関連分類
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