CDK2-IN-8
CDK2-IN-8 is a potent CDK2 inhibitor with an IC50 of 1.74 µM. CDK2-IN-8 shows antiproliferative activity. CDK2-IN-8 has the potential for the research of melanoma.
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- CAS. Nr.: 2919216-36-5
- Formel: C22H25N5O3
- Molecular Weight:407.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
CDK2 1.74 μM (IC50) |
In Vitro
CDK2-IN-8 (compound 8a) shows antiproliferative activity with IC50s of 6.22, 37.24 µM for MDA-MB-435, WI-38 cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2919216-36-5
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Molecular Weight 407.47
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Formel C22H25N5O3
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SMILES
O=C(NN1C(COC2=CC=CC=C2)=NC3=C(C=CC=C3)C1=O)CN4CCN(C)CC4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)