HDAC1-IN-4
HDAC1-IN-4 (JX34) is a potent Plasmodium falciparum HDAC1 inhibitor shows antimalarial activity (IC50 < 5 nM) and lower cytotoxicity.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2482998-39-8
- Formel: C21H24BrClN6O2
- Molecular Weight:507.81
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | IC50 |
0.72 μM
Compound: JX34
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Cytotoxicity against HEK293T cells incubated for 72 hrs by CCK-8 assay
Cytotoxicity against HEK293T cells incubated for 72 hrs by CCK-8 assay
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[PMID: 35175762] |
| HepG2 | IC50 |
0.75 μM
Compound: JX34
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Cytotoxicity against human HepG2 cells incubated for 72 hrs by CCK-8 assay
Cytotoxicity against human HepG2 cells incubated for 72 hrs by CCK-8 assay
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[PMID: 35175762] |
Chemical Information
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CAS. Nr. 2482998-39-8
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Molecular Weight 507.81
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Formel C21H24BrClN6O2
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SMILES
O=C(C1=CN=C(N(CC2)CC32CN(CC4=CN(C)C5=C4C=CC(Br)=C5)C3)N=C1)NO.[H]Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HDAC1-IN-4 Related Classifications
HY-144298 Related Classifications
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