DdBIC
DdBIC is a pyroptosis inducer. DdBIC binds to Nur77 and triggers its translocation to mitochondria, activates SDHA to deplete succinyl-CoA, disrupts heme homeostasis, induces electron leakage, and elicits mitochondrial ROS production. DdBIC induces mitochondrial ROS that oxidatively activates OMA1, promotes OPA1 cleavage and its release into the cytoplasm, activates the integrated stress response via PERK, and ultimately activates granzyme B to cleave GSDMC. DdBIC can be used for the study of melanoma.
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- CAS No.: 3085711-53-8
- Formule: C20H30N2O2
- Masse moléculaire:330.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Activité biologique
Chemical Information
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CAS No. 3085711-53-8
-
Masse moléculaire 330.46
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Formule C20H30N2O2
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SMILES
O=C(C1=CC=C2NC=NC2=C1)OCCCCCCCCCCCC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DdBIC Related Classifications
HY-180786 Related Classifications
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