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Genistein

(Synonyms: NPI 031L)
91 Cited Publications
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Based on 91 publication(s) in Google Scholar

Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.

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  • Pureza: 99.82%
  • No. CAS: 446-72-0
  • Fòrmula: C15H10O5
  • Peso molecular:270.24
  • Almacenamiento:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • Genistein Chemical Structure
    Genistein Chemical Structure
  • Experimental Validation Results for Genistein
  • Experimental Validation Results for Genistein
  • Experimental Validation Results for Genistein
  • Experimental Validation Results for Genistein
  • Experimental Validation Results for Genistein
No. CAS: 446-72-0
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Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
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  • Genistein Chemical Structure
    Genistein Chemical Structure
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    Genistein purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2025 Oct 21;10(1):349. [Abstract]

    Customer Validation
     Analysis of the cellular uptake pathways of OVA PCD. Ethamilamiline (EIPA), genistein (GEN, 200 μM), and chlorpromazine (CPZ), pretreated for 4 h, subsequently incubated with FITC-labeled OVA PCD for 12 h were used to inhibit macropinocytosis, caveolin-mediated endocytosis, and clathrin-mediated endocytosis, respectively (n = 5).

  • 1/16

    Genistein purchased from MedChemExpress. Usage Cited in: Nat Immunol. 2025 Apr 11. [Abstract]

    Customer Validation
     Flow cytometry analysis of FDG MFI of neutrophils treated with dimethyl sulfoxide (DMSO) or different metabolites; the neutrophil FDG MFI ratio of metabolites relative to DMSO was calculated (n = 3).

  • 1/16

    Genistein purchased from MedChemExpress. Usage Cited in: Nat Biomed Eng. 2024 Nov;8(11):1469-1482. [Abstract]

    Customer Validation
     Cellular uptake pathway of different formulations. Cells were pretreated 2h with methyl-β-cyclodextrin (MCD), genistein (Gen, 200 µM), amiloride (AMI) or chlorpromazine (CPZ), to block lipid raft, caveolae-mediated endocytosis, micropinocytosis and clathrin-mediated endocytosis, respectively.

  • 1/16

    Genistein purchased from MedChemExpress. Usage Cited in: Bioact Mater. 2021 Jan 14;6(7):2158-2172. [Abstract]

    Customer Validation
     Transcytosis efficiency of FITC-labelled aPD/IND@MON-IgG and aPD/IND@MON-aANN at 30 min and 60 min in the transcytosis model pretreated with or without 200 μM genistein (endocytic pathway inhibitor) or 20 μM EXO1 (exocytic pathway inhibitor) for 2h.

  • 1/16

    Genistein purchased from MedChemExpress. Usage Cited in: Nat Nanotechnol. 2020 Dec;15(12):1043-1052. [Abstract]

    Customer Validation
     Flow cytometry measured the FITC MFI of CD11c+ BMDCs for BMDCs incubated with F7-PEI/FITC-OVA or F13-PEI/FITC-OVA, w/wo adding indicated endocytosis inhibitors (n = 3). BMDCs were incubated with genistein (700μM) for 30min before the addition of F7-PEI/OVA-FITC or F13-PEI/OVA-FITCNPs.

  • Genistein