Anticancer agent 29
Anticancer agent 29 (Compd E/Z-6f) is an anticancer agent, with IC50 values of 0.054 μM, 0.127 μM, 0.129 μM, 0.396 μM for CDK2, CDK1, CDK4 and CDK6, respectively.
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- No. CAS: 2907774-89-2
- Fòrmula: C22H15ClFNO
- Peso molecular:363.81
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
[1].|
CDK2/cyclinE 0.054 μM (IC50) |
CDK1/cyclinB1 0.127 μM (IC50) |
CDK4 0.129 μM (IC50) |
CDK6 0.396 μM (IC50) |
Chemical Information
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No. CAS 2907774-89-2
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Peso molecular 363.81
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Fòrmula C22H15ClFNO
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SMILES
O=C1/C(C2=CC=CC=C2N1CC3=CC=C(C=C3)F)=C/C4=CC=C(C=C4)Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 29 Related Classifications
HY-115942 Related Classifications
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