CCT68127
CCT68127 is an orally active CDK inhibitor. CCT68127 can be used in anti-cancer research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 660822-23-1
- Fòrmula: C19H27N7O
- Peso molecular:369.46
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
|
CDK2 |
CDK7 |
CDK9 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | IC50 |
1.3 μM
Compound: alphaSbetaR-21, CCT68127
|
Inhibition of CDK7 in human HT29 cells assessed as reduction in RNA polymerase 2 expression
Inhibition of CDK7 in human HT29 cells assessed as reduction in RNA polymerase 2 expression
|
[PMID: 21982796] |
| HT-29 | IC50 |
107 nM
Compound: alphaSbetaR-21, CCT68127
|
Inhibition of CDK9 in human HT29 cells assessed as reduction in RNA polymerase 2 expression
Inhibition of CDK9 in human HT29 cells assessed as reduction in RNA polymerase 2 expression
|
[PMID: 21982796] |
Chemical Information
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No. CAS 660822-23-1
-
Peso molecular 369.46
-
Fòrmula C19H27N7O
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SMILES
C[C@@H](O)[C@@H](NC1=NC(NCC2=CC=CN=C2)=C3N=CN(C(C)C)C3=N1)CC
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Synonyms
αSβR-21
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)