DdBIC
DdBIC is a pyroptosis inducer. DdBIC binds to Nur77 and triggers its translocation to mitochondria, activates SDHA to deplete succinyl-CoA, disrupts heme homeostasis, induces electron leakage, and elicits mitochondrial ROS production. DdBIC induces mitochondrial ROS that oxidatively activates OMA1, promotes OPA1 cleavage and its release into the cytoplasm, activates the integrated stress response via PERK, and ultimately activates granzyme B to cleave GSDMC. DdBIC can be used for the study of melanoma.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3085711-53-8
- Fòrmula: C20H30N2O2
- Peso molecular:330.46
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Ver todos los productos específicos de isoformas Nuclear Hormone Receptor 4A/NR4A
MoreVer todos los productos específicos de isoformas Caspase
More
Actividad biológica
Chemical Information
-
No. CAS 3085711-53-8
-
Peso molecular 330.46
-
Fòrmula C20H30N2O2
-
SMILES
O=C(C1=CC=C2NC=NC2=C1)OCCCCCCCCCCCC
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DdBIC Related Classifications
HY-180786 Related Classifications
Powered by Bioz