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Referencia número: HY-112542

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Nemadectin

(Synonyms: CL-287088; LL-F28249 α)

Revisión del cliente

Based on 1 Customer Validation

Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity.

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 99.79%
No. CAS: 102130-84-7
Fòrmula: C₃₆H₅₂O₈
Peso molecular:612.79

Almacenamiento:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Nemadectin Chemical Structure

No. CAS: 102130-84-7

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Precio

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Cantidad

Amount: USD 0.00

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vivo
Chemical Information
Solvente y solubilidad
- In Vitro
Pureza y Documentación
Referencias
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Nemadectin (CL-287088), an orally active broad-spectrum endectocide, is highly efficacious against natural infections of all the major canine gastrointestinal helminthes. Anthelmintic activity^[1].

IC₅₀ & Target

Mite

Ver todos los productos específicos de isoformas Parasite :

Ver todos los productos específicos de isoformas Antibiotic :

In Vivo

Nemadectin is highly effective at 0.6 mg/kg BW against natural infections of all major species of canine intestinal helminths, when administered as a single oral dose, either as a liquid or a tablet^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 102130-84-7
Appearance Solid
Peso molecular 612.79
Fòrmula C₃₆H₅₂O₈
Color White to off-white
SMILES

C/C(C[C@H](/C=C/C=C1CO[C@]([H])([C@@H](C(C)=C[C@]2(C3=O)[H])O)[C@@]\12O)C)=C\C[C@@]4([H])O[C@]5(O[C@@H]([C@H]([C@H](C5)O)C)/C(C)=C/C(C)C)C[C@](O3)([H])C4
Synonyms

CL-287088; LL-F28249 α
Structure Classification
- Antibiotics
- Macrolide Antibiotics
Initial Source
- Microorganisms
Streptomyces microflavus neau3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

DMSO : 100 mg/mL (163.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.6319 mL

8.1594 mL

16.3188 mL

5 mM

0.3264 mL

1.6319 mL

3.2638 mL

10 mM

0.1632 mL

0.8159 mL

1.6319 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (280 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Doscher ME, et al. Efficacy of nemadectin, a new broad-spectrum endectocide, against natural infections of canine gastrointestinal helminths. Vet Parasitol. 1989;34(3):255-259. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.6319 mL	8.1594 mL	16.3188 mL	40.7970 mL
	5 mM	0.3264 mL	1.6319 mL	3.2638 mL	8.1594 mL
	10 mM	0.1632 mL	0.8159 mL	1.6319 mL	4.0797 mL
	15 mM	0.1088 mL	0.5440 mL	1.0879 mL	2.7198 mL
	20 mM	0.0816 mL	0.4080 mL	0.8159 mL	2.0399 mL
	25 mM	0.0653 mL	0.3264 mL	0.6528 mL	1.6319 mL
	30 mM	0.0544 mL	0.2720 mL	0.5440 mL	1.3599 mL
	40 mM	0.0408 mL	0.2040 mL	0.4080 mL	1.0199 mL
	50 mM	0.0326 mL	0.1632 mL	0.3264 mL	0.8159 mL
	60 mM	0.0272 mL	0.1360 mL	0.2720 mL	0.6800 mL
	80 mM	0.0204 mL	0.1020 mL	0.2040 mL	0.5100 mL
	100 mM	0.0163 mL	0.0816 mL	0.1632 mL	0.4080 mL

Keywords

MOQ

Minimum order quantity

100 mg

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Actividad biológica
- Descripciòn
- IC₅₀ & Target
- In Vivo
Chemical Information
Solvente y solubilidad
- In Vitro
Pureza y Documentación
Referencias

Nombre del producto:
Referencia número:
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Nemadectin

Anti-Infection Compound Library

Natural Product Library

Macrocyclic Compound Library

Antibiotics Library

Antiparasitic Compound library

Microbial Metabolite Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Natural Product Library Plus

Natural Product and Natural Product-Like Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Natural Product Diversity Scaffold Library

Mass Spectrometry Natural Product Library

Ver todos los productos específicos de isoformas Parasite

Ver todos los productos específicos de isoformas Antibiotic

Actividad biológica

Chemical Information

Solvente y solubilidad

Pureza y Documentación

Referencias

Help & FAQs

Complete Stock Solution Preparation Table

Nemadectin

Anti-Infection Compound Library

Natural Product Library

Macrocyclic Compound Library

Antibiotics Library

Antiparasitic Compound library

Microbial Metabolite Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Natural Product Library Plus

Natural Product and Natural Product-Like Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Natural Product Diversity Scaffold Library

Mass Spectrometry Natural Product Library

Ver todos los productos específicos de isoformas Parasite

Ver todos los productos específicos de isoformas Antibiotic

Actividad biológica

Chemical Information

Solvente y solubilidad

Pureza y Documentación

Referencias

Help & FAQs

Complete Stock Solution Preparation Table

Nemadectin Related Classifications

HY-112542 Related Classifications