X-370
X-370 is a PI3Kδ inhibitor (IC50 = 7 nM). X-370 inhibits the survival of leukemia cells, inducing G1 arrest and apoptosis. X-370 blocks PDK1 binding and phosphorylation of MEK1/2, eliminating Akt and Erk1/2 signaling. X-370 can be used in research on B-cell acute lymphoblastic leukemia (B-ALL).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1280725-80-5
- Fòrmula: C27H31F2N9O2
- Peso molecular:551.59
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 1280725-80-5
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Peso molecular 551.59
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Fòrmula C27H31F2N9O2
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SMILES
FC(F)C1=NC2=C(N1C3=NC(N4CCOCC4)=NC5=C3N=CN5C6CCN(C(N7CCCC7)=O)CC6)C=CC=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
X-370 Related Classifications
HY-12482 Related Classifications
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