VAMP5 - vesicle associated membrane protein 5 Gene

Homo sapiens

Gene ID: 10791 | Gene type: protein coding

About VAMP5

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:85,584,431-85,593,406 (from NCBI)

This gene has 2 transcripts (splice variants), 163 orthologues and 10 paralogues. Ubiquitous expression in lung (RPKM 45.4), fat (RPKM 40.5) and 24 other tissues.

Summary

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis. [provided by RefSeq, Jul 2008]

VAMP5 Products(1)

mRNA	Protein	Name
NM_006634.3	NP_006625.1	vesicle-associated membrane protein 5

VAMP5 Protein Structure

Synaptobrevin

0
100
116 a.a.

Protein Preferred Names

Protein Names

vesicle-associated membrane protein 5

VAMP-5

Related Diseases

Diseases

Alias

Foodborne Botulism

Botulism	Botulism Poisoning
Intoxication With Clostridium Botulinum Toxin	Wound Botulism
Food Poisoning Due To Clostridium Botulinum	Infection Due To Clostridium Botulinum
Infant Botulism	Intoxication Botulism
Botulism, Infantile	Clostridium Botulinum Poisoning
Botulism Nos

Infant Botulism

Infant Intestinal Botulism	Infant Intestinal Toxemia Botulism
Infant Intestinal Toxin-Mediated Botulism	Infantile Botulism
Botulism, Infantile

Hirschsprung Disease 1

Hirschsprung Disease	Aganglionic Megacolon
Hscr	Hirschsprung'S Disease
Congenital Megacolon	Congenital Intestinal Aganglionosis
Colonic Aganglionosis	Hirschsprung Disease, Susceptibility To, 1
Hirschsprung Disease, Protection Against	HSCR1
Mgc	Pelvirectal Achalasia
Total Intestinal Aganglionosis	Megacolon, Aganglionic
Macrocolon	Hscr 1
Hirschsprung Disease Type 1	Hirschsprung Disease, Type 1
Congenital Dilatation Of Colon	Aganglionosis
Congenital Aganglionic Megacolon	Aganglionosis Of Colon
Bowel Aganglionosis	Colon Aganglionosis
Hirschsprung Megacolon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15597	VAMP5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	VAMP5	VGNC	VGNC:78753
Canis familiaris	VAMP5	VGNC	VGNC:48225
Felis catus	VAMP5	VGNC	VGNC:66912
Bos taurus	VAMP5	VGNC	VGNC:36759
Mus musculus	VAMP5	MGD	MGI:1858622
Rattus norvegicus	VAMP5	RGD	RGD:620419

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