Npy - neuropeptide Y Gene
Also Known as 0710005A05Rik
Species: Mus musculus
Summary
This gene encodes a neuropeptide that plays a pivotal role in many physiological functions such as food intake, energy homeostasis, circadian rhythm, and cognition. The encoded protein precursor undergoes proteolytic processing to generate the biologically active peptide. Mice lacking the encoded protein exhibit mild seizures occasionally and become hyperphagic following food deprivation. A deficiency of the encoded protein partially prevents mice lacking Leptin from becoming obese. [provided by RefSeq, Oct 2015]
Npy Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_023456.3 | NP_075945.1 | pro-neuropeptide Y preproprotein |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables G protein-coupled receptor binding |
IDA
IDA: Inferred from direct assay
|
10698177 | MGI |
| enables G protein-coupled receptor binding |
IGI
IGI: Inferred from genetic interaction
|
9623984 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within regulation of blood pressure |
IDA
IDA: Inferred from direct assay
|
9623984 | MGI |
| involved in synaptic signaling via neuropeptide |
EXP
EXP: Inferred from Experiment
|
22190627 | MGI |
| involved in synaptic signaling via neuropeptide |
IDA
IDA: Inferred from direct assay
|
22190627 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| is active in GABA-ergic synapse |
EXP
EXP: Inferred from Experiment
|
22190627 | MGI |
| is active in GABA-ergic synapse |
IDA
IDA: Inferred from direct assay
|
22190627 | MGI |
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
24582971 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
pro-neuropeptide Y |
|