1. Gene
  2. Il13 - interleukin 13 Gene

Il13 - interleukin 13 Gene

Mus musculus

Also known as Il-13

Gene ID: 16163 | Gene type: protein coding

About Il13

Chromosome 11: 53,522,151-53,525,529 reverse strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 88 orthologues and is associated with 55 phenotypes. Biased expression in thymus adult (RPKM 2.8), testis adult (RPKM .6) and 2 other tissues.

Summary

Predicted to enable interleukin-13 receptor binding activity. Involved in positive regulation of cold-induced thermogenesis and positive regulation of macrophage activation. Acts upstream of or within cellular response to cytokine stimulus; inflammatory response; and positive regulation of immune effector process. Located in cytoplasm; external side of plasma membrane; and extracellular space. Is expressed in gut; liver; male reproductive gland or organ; and thymus. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); diffuse scleroderma; lung disease (multiple); and nose disease (multiple). Orthologous to human IL13 (interleukin 13). [provided by Alliance of Genome Resources, Apr 2022]

Il13 Products(1)

mRNA Protein Name
NM_008355.3 NP_032381.1 interleukin-13 precursor

Il13 Protein Structure

IL13

IL13: pfam03487 (20 - 129)

  • 0
  • 100
  • 131 a.a.
Protein Preferred Names Protein Names

interleukin-13

T-cell activation protein P600

Recombinant Il13 Proteins

Cat. No. Product Name Accession Purity
HY-P7076A IL-13 Protein, Mouse (CHO, His) P20109 (P22-F131) ≥95%
HY-P7569 Recombinant Mouse Interleukin-13 P20109 /
HY-P70460 IL-13 Protein, Mouse P20109 (S26-F131) ≥95%
HY-P72595 IL-13 Protein, Mouse (HEK293, His) P20109 (P22-F131) ≥95%
HY-P73168 IL-13 Protein, Mouse (HEK293) P20109 (A19-F131) ≥95%
HY-P700192AF Animal-Free IL-13 Protein, Mouse (His) P20109 (P22-F131) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Il13 NCBI NCBI:3596
Canis familiaris Il13 NCBI NCBI:442990
Macaca fascicularis Il13 NCBI NCBI:102125887
Rattus norvegicus Il13 NCBI NCBI:116553