HDAC6/HSP90-IN-3
HDAC6/HSP90-IN-3 (Compound 17) is an orally active dual histone deacetylase 6 (HDAC6) and heat shock protein 90 (HSP90) inhibitor with IC50 values of 28 nM and 0.88 μM, respectively. HDAC6/HSP90-IN-3 is promising for research of malignant tumors such as prostate cancer.
For research use only. We do not sell to patients.
- Formula: C23H23ClN6O3
- Molecular Weight:466.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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HDAC6 28 nM (IC50) |
HSP90 0.88 μM (IC50) |
Chemical Information
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Molecular Weight 466.92
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Formula C23H23ClN6O3
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SMILES
CC1=CN=C(CN2C3=NC(N)=NC(Cl)=C3C(CC4=CC=C(C(NO)=O)C=C4)=C2)C(C)=C1OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HDAC6/HSP90-IN-3 Related Classifications
HY-175467 Related Classifications
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