HDAC6-IN-54
HDAC6-IN-54 (Compound 9m) is a highly selective HDAC6 (histone deacetylase 6) inhibitor with an IC50 value of 0.021 μM. HDAC6-IN-54 blocks the activation of the NLRP3 inflammasome, which alleviates symptoms of NLRP3 inflammasome-related diseases such as acute peritonitis, inflammatory bowel disease, and psoriasis.
For research use only. We do not sell to patients.
- Formula: C23H20F2N4O
- Molecular Weight:406.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC6 0.021 μM (IC50) |
Chemical Information
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Molecular Weight 406.43
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Formula C23H20F2N4O
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SMILES
FC1=C(C(NNCC)=O)C=C(F)C(CN2C3=CC=CC=C3C=CC4=C2C=NC=C4)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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