HQ005
Based on 1 Customer Validation
HQ005 is a potent CCNK degrader with an DC50 value of 0.041 µM. HQ005 is a molecular-glue degrader that mediates interactions between target proteins and components of the ubiquitin-proteasome system to cause selective protein degradation.
For research use only. We do not sell to patients.
- Purity: 98.56%
- CAS No.: 2750644-31-4
- Formula: C15H15N5O2S2
- Molecular Weight:361.44
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
IC50: 0.041 µM (CCNK)[1]
Chemical Information
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CAS No. 2750644-31-4
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Appearance Solid
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Molecular Weight 361.44
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Formula C15H15N5O2S2
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Color White to off-white
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SMILES
O=C(CC1=CSC(NC2=CC=CC(CO)=N2)=N1)NC3=NC=C(C)S3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)