CDK4-IN-7
CDK4-IN-7 is a CDK4 inhibitor with an IC50 of 26 nM. CDK4-IN-7 shows selectivity for CDK1, with an IC50 of 4.2262 μM. CDK4-IN-7 can be used in cancer research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3113087-01-4
- 分子式: C20H28F2N6O2S
- 分子量:454.54
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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CDK4 26 nM (IC50) |
CDK1 4.2262 μM (IC50) |
CDK4-IN-7 (Compound 5) potently inhibits CDK4 with an IC50 of 26 nM and shows 162.5-fold selectivity for CDK4 over CDK1 in a biochemical kinase assay measuring retinoblastoma protein Ser780 phosphorylation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3113087-01-4
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分子量 454.54
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分子式 C20H28F2N6O2S
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SMILES
CC1=CC2=CN=C(N[C@H]3[C@H](F)CN(S(C4CC4)(=O)=O)CC3)N=C2N1[C@@H]5CCNC[C@@H]5F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CDK4-IN-7 関連分類
HY-184444 関連分類
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