Viquidacin
Viquidacin (NXL 101) is an antibiotic with inhibitory activity against topoisomerase IV and DNA gyrase. Viquidacin exhibits antibacterial activity against gram positive bacterial by inhibiting the supercoiling, decatenation and relaxation in strains Staphylococcus aureus and Escherichia coli in micromolar levels. Viquidacin inhibits S. aureus wildtype and mutants with MIC of 2-128 mg/L.
For research use only. We do not sell to patients.
- CAS No.: 904302-98-3
- Formula: C25H29FN2O4S2
- Molecular Weight:504.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
23.6 μM
Compound: 2, NXL-101, AVE-4221
|
Inhibition of human ERG channel in HEK293 cells by voltage-gated patch clamp technique
Inhibition of human ERG channel in HEK293 cells by voltage-gated patch clamp technique
|
[PMID: 23566517] |
Chemical Information
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CAS No. 904302-98-3
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Molecular Weight 504.64
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Formula C25H29FN2O4S2
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SMILES
[H][C@@](C1)(C(O)=O)[C@@](CC[C@]([H])(O)C2=C(F)C=NC3=C2C=C(OC)C=C3)([H])CCN1CCSC4=CC=CS4
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Synonyms
NXL 101
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Viquidacin Related Classifications
HY-14780 Related Classifications
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