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Cytarabine

(Synonyms: Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C)
100 Cited Publications
고객리뷰

Based on 100 publication(s) in Google Scholar

Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine has antiviral effects against HSV. Cytarabine shows anti-orthopoxvirus activity.

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  • Purity: 99.98%
  • CAS No.: 147-94-4
  • 화학식: C9H13N3O5
  • 분자량:243.22
  • 보관:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 2 years , -20°C, 1 year
  • Cytarabine Chemical Structure
    Cytarabine Chemical Structure
  • Experimental Validation Results for Cytarabine
  • Experimental Validation Results for Cytarabine
  • Experimental Validation Results for Cytarabine
  • Experimental Validation Results for Cytarabine
  • Experimental Validation Results for Cytarabine
CAS No.: 147-94-4
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  • Cytarabine Chemical Structure
    Cytarabine Chemical Structure
    1/16
  • 1/16

    Cytarabine purchased from MedChemExpress. Usage Cited in: Toxicol Appl Pharmacol. 2025 May:498:117305. [Abstract]

    Customer Validation
     FKA (Flavokawain A; HY-N2420) decreases the viability in AML cell lines. MV4-11, MOLM-13, THP-1, and U937 cells were treated with or without various concentrations of FKA (2.5, 5, 10, and 20 μg/mL) for 24 and 48 h, and cell viability was detected by the MTS assay. Treatment with Cytarabine (HY-13605; 7.3 μg/mL) was used as a positive control.

  • 1/16

    Cytarabine purchased from MedChemExpress. Usage Cited in: Toxicol Appl Pharmacol. 2025 May:498:117305. [Abstract]

    Customer Validation
     FKA (Flavokawain A; HY-N2420) targets primary AML blasts. Samples from AML patients were treated with or without various concentrations of FKA (2.5, 5, 10, and 20 μg/mL) for 48 h, and cell viability was detected by the MTS assay. Treatment with Cytarabine (HY-13605) was used as a positive control. Data were shown as mean ± SD from at least three independent experiments.

  • 1/16

    Cytarabine purchased from MedChemExpress. Usage Cited in: Cell Rep Med. 2024 Sep 27:101770. [Abstract]

    Customer Validation
     Cell viability of WiT49-parental and WiT49-PRC-1 cells treated with cytarabine. IC50 is shown in the figure. The WiT49-PRC-1 cells are 100-fold more sensitive to cytarabine and 20-fold more sensitive to alisertib than the parental WiT49 cells.

  • 1/16

    Cytarabine purchased from MedChemExpress. Usage Cited in: Leukemia. 2021 Oct;35(10):2827-2839. [Abstract]

    Customer Validation
     TF-1 clones are incubated with 2 µM Cytarabine (araC) for up to 10 or 12 h, and cleaved caspase-3 is detected by immunoblot analysis.

  • 1/16

    Cytarabine purchased from MedChemExpress. Usage Cited in: Leukemia. 2021 Oct;35(10):2827-2839. [Abstract]

    Customer Validation
     TF-1 clones were incubated with 2 µM araC or 1 µM DNR for up to 10 or 12 h, respectively, and cleaved caspase-3 was detected by immunoblot analysis. GAPDH was used as loading control.

  • Cytarabine