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Cat. No.: HY-114338B

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Dalpiciclib isethionate

(Synonyms: SHR-6390 isethionate)

2 Cited Publications

고객리뷰

Based on 2 publication(s) in Google Scholar

Dalpiciclib (isethionate) is a CDK4/6 inhibitor. Dalpiciclib (isethionate) inhibits the kinase activity of CDK4 and CDK6, thereby blocking the G1-to-S phase transition of the cell cycle and suppressing abnormal cell proliferation. Dalpiciclib (isethionate) can be used for the study of breast cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1980822-14-7
화학식: C₂₇H₃₆N₆O₆S
분자량:572.68

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Dalpiciclib isethionate Chemical Structure

CAS No.: 1980822-14-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Biological Activity

제품 설명

IC₅₀ & Target^[1]

CDK4

CDK6

All CDK Isoforms :

Chemical Information

CAS No. 1980822-14-7
분자량 572.68
화학식 C₂₇H₃₆N₆O₆S
SMILES

O=C1C(C(C)=O)=C(C)C2=C(N1C3CCCC3)N=C(NC4=NC=C(C5CCNCC5)C=C4)N=C2.O=S(O)(CCO)=O
Synonyms

SHR-6390 isethionate
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Cell Death Dis

The CDK4/6 inhibitor dalpiciclib augments the antitumor efficacy of enzalutamide in preclinical models of castration-resistant prostate cancer through inhibition of MCM4-mediated DNA replication. [Abstract]

2026 Jun 5. PMID: 42248826
Leuk Res Rep

2025 Dec 20.

순도&문서

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. ZHU Xiaoyu, et al. Use of Composition Containing CDK4/6 Inhibitor in Combination with Anastrozole in Preparation of Medicament for Treating Tumor Diseases. WO2020/156446 A1. World Intellectual Property Organization (WIPO). August 6, 2020.

Calculators

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Concentration _(start) Concentration _(start)

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Dalpiciclib isethionate

2 Cited Publications

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Publications (2)
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Dalpiciclib isethionate

Publications Citing Use of MedChemExpress (MCE) Dalpiciclib isethionate

All CDK Isoforms

Biological Activity

Chemical Information

Publications (2)

순도&문서

References

Calculators

Help & FAQs

Dalpiciclib isethionate Related Classifications

HY-114338B Related Classifications