AB3145
AB3145 is a selective Brd4 BromoTag PROTAC degrader (DC50: 120-140 pM). AB3145 promotes the ubiquitination and degradation of Brd4. AB3145 can be used in cancer research.
(Pink: BRD4 ligand (HY-147046) and no Target protein ligand; Blue: Cereblon ligand (HY-W998346) and VHL ligand (HY-112078); Black: linker and linker).
For research use only. We do not sell to patients.
- Formula: C76H95ClFN11O17S2
- Molecular Weight:1553.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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BRD4 120-140 pM (DC50) |
Chemical Information
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Molecular Weight 1553.21
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Formula C76H95ClFN11O17S2
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SMILES
CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@]([C@@H](CC)C(OCCOCCOCCOCC(COCCOCCOCCNC4=C(F)C=C(C(N(C5C(NC(CC5)=O)=O)C6=O)=O)C6=C4)(C)COCC(N[C@@H](C(C)(C)C)C(N7[C@H](C(N[C@@H](C)C8=CC=C(C9=C(C)N=CS9)C=C8)=O)C[C@@H](O)C7)=O)=O)=O)([H])C%10=NN=C(C)N2%10
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AB3145 Related Classifications
HY-180923 Related Classifications
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