206 Results for "

Tissue specific

" in MedChemExpress (MCE) Product Catalog:
Products (206)

206 Results for "Tissue specific" in MCE Product Catalog:

82
82 Publications Verification
Cat. No.: HY-W009724
CAS No.: 524-95-8
Synonyms: 2-APB
2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca 2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-P74743
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MRAP; Fat Cell-specific Low Molecular Weight Protein; Prev. C21orf61; Fat Tissue-specific Low MW Protein; FALP; Chromosome 21 Open Reading Frame 61; B27; GCCD2; MRAP1; Melanocortin 2 Receptor Accessory Protein; Melanocortin-2 Receptor Accessory Protein
Species:  
Human
Source:  
HEK293
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P4094
CAS No.: 1052692-86-0
Synonyms: Cardiac targeting peptide
Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease

CTP (cardiac targeting peptide) can transduce cardiomyocytes in vitro. CTP leads to efficient and specific transduction of heart tissue in mice model. CTP can be reversibly linked (e.g. via enolases, thiol groups) to cargo (e.g. miRNAs) for delivery specifically to cardiomyocytes over all other organs .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-125039
CAS No.: 1287585-40-3
Purity:  99.57%
N-Acetyl lysyltyrosylcysteine amide is a potent, reversible, specific, and non-toxic tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO generation of toxic oxidants in vivo. N-Acetyl lysyltyrosylcysteine amide reduces neuronal damage and preserves brain tissue and neurological function in the stroked brain. N-Acetyl lysyltyrosylcysteine amide inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL oxidation .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P72153
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; Connective Tissue Growth Factor; IGFBP-8; Hypertrophic Chondrocyte-specific Protein 24; NOV2; Insulin-Like Growth Factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Human
Source:  
E. coli
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P72154
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; Connective Tissue Growth Factor; IGFBP-8; Hypertrophic Chondrocyte-specific Protein 24; NOV2; Insulin-Like Growth Factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-118716
CAS No.: 105650-23-5
Purity:  99.93%
Synonyms: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is the most abundant of generation of heterocyclic amines (HCA), resulted in the cooking of meat . DNA damaging and mutagenic activities. PhIP also has oestrogenic activity that could contribute to its tissue specific carcinogenicity .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W020215
CAS No.: 99-14-9
Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a Ki value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W250150
CAS No.: 5486-84-0
Research Areas:  

Others

Fast blue bb salt (hemi(zinc chloride) salt is a water-soluble dye commonly used as a histological stain in various biological applications such as staining cellular components or detecting enzyme activity. Fast blue BB salt has a unique Chemical properties that allow it to bind to specific proteins to form a blue product that can be detected by microscopy or spectrophotometry. This makes it a useful tool for visualizing and quantifying target proteins in tissue samples or cell cultures.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-D1719A
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Cypate is a near-infrared fluorescent dye that belongs to the family of photosensitizers. Cypate has high photostability and optical properties, and is often used in near-infrared optical imaging, as well as optical imaging, tumor marking, and drug delivery. In addition, Cypate is also used as a molecular probe and combined with targeting molecules (such as CBT or small interfering RNA) to achieve efficient detection and imaging of specific cells or tissues .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P1597
CAS No.: 86555-35-3
Target:  

PKA PKC

Research Areas:  

Cancer

Malantide is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts . Malantide is also an efficient substrate for PKC with a Km of 16 μM .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-D2186
CAS No.: 2095485-22-4
BTD probe-1 is a benzothiazine-based chemoproteomic probe and selective protein S-sulfenic acid (Cys-SOH) labeling agent. BTD probe-1 labels protein S-sulfenic acids in vitro in cell and tissue samples, and in situ in intact cells, enabling detection or enrichment of modified proteins/peptides. BTD probe-1 exhibits no cytotoxicity in cells at concentrations ≤1 mM. BTD probe-1 enables global, site-specific mapping and quantification of cysteine S-sulfenylation in complex proteomes with lower input material .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P70106
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; Connective Tissue Growth Factor; IGFBP-8; Hypertrophic Chondrocyte-specific Protein 24; NOV2; Insulin-Like Growth Factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Human
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P70602
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; Connective Tissue Growth Factor; IGFBP-8; Hypertrophic Chondrocyte-specific Protein 24; NOV2; Insulin-Like Growth Factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Human
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P78104
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CCN2; CCN Family Member 2; Prev. CTGF; IBP-8; IGFBP8; SEMDLSL; Connective Tissue Growth Factor; IGFBP-8; Hypertrophic Chondrocyte-specific Protein 24; NOV2; Insulin-Like Growth Factor-Binding Protein 8; KMD; IGF-Binding Protein 8; Cellular Communication N
Species:  
Human
Source:  
HEK293
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-123581
CAS No.: 81810-66-4
Purity:  98.00%
Quinocetone is an orally active animal feed additive used to increase the meat production of livestock and poultry. Quinocetone exhibits antibacterial activity against a variety of pathogenic microorganisms. Quinocetone exhibits tissue-specific (liver, lymphocyte) toxicity. Quinocetone induces autophagy in cells through the ATF6/DAPK1 pathway. Quinocetone activates the NF-κB and iNOS pathways, leading to cell apoptosis, hepatocyte vacuolar degeneration and fibrosis. Quinocetone can inhibit Nrf2/HO-1 and induce the generation of reactive oxygen species (ROS), leading to oxidative stress and DNA damage .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N1964
CAS No.: 77-06-5
Synonyms: Gibberellin A3
Gibberellic acid (GA3) is a natural plant growth regulator with oral bioactivity. Gibberellic acid governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid can be used in studies of plant growth, metabolism, and abiotic stress responses .
loading...
    loading...
Cat. No.: HY-P5623A
CAS No.: 1186105-01-0
Synonyms: RVG29-Cys; RDP-Cys; Rabies Virus Glycoprotein-29-Cys
Target:  

RABV

Research Areas:  

Others

RVG-Cys (RVG29-Cys) is a peptide derived from rabies virus glycoprotein (RVG29) with Cys attached to facilitate subsequent conjugation. RVG-Cys enhances the specific targeted delivery of proteins in brain tissue and neurons .
loading...
    loading...
Cat. No.: HY-165740
CAS No.: 65988-71-8
Synonyms: Disialoganglioside GD2
Target:  

Apoptosis

Research Areas:  

Cancer

Ganglioside GD2 (Disialoganglioside GD2) is a tumor-associated antigen. Ganglioside GD2 shows limited expression in normal tissues but is overexpressed in multiple tumor types, and thus can serve as a target in cancer. Ganglioside GD2 is associated with tumor development and malignant phenotypes, and its mechanism of action relies on enhancing cell proliferation, motility, migration, adhesion and invasion, with specific effects depending on the tumor type .
loading...
    loading...
Cat. No.: HY-P2752
CAS No.: 9004-02-8
Synonyms: LPL
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

Lipoprotein lipase, Pseudomonas sp (LPL) is a multifunctional enzyme from adipose tissue, heart and skeletal muscle, islets and macrophages. Lipoprotein lipase promotes normal lipoprotein metabolism, delivery and utilization of tissue-specific substrates. Lipoprotein lipase catalyzes the rate-limiting step of lipids in blood circulation .
loading...
    loading...